{"id":"W2748021571","doi":"10.1002/hep4.1086","title":"High‐mobility‐group protein 2 regulated by microRNA‐127 and small heterodimer partner modulates pluripotency of mouse embryonic stem cells and liver tumor initiating cells","year":2017,"lang":"en","type":"article","venue":"Hepatology Communications","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute on Alcohol Abuse and Alcoholism; National Institutes of Health; School of Medicine, New York University; York University; National Institute of Diabetes and Digestive and Kidney Diseases; University of Minnesota; National Institute of Environmental Health Sciences; U.S. Department of Veterans Affairs","keywords":"SOX2; Embryonic stem cell; Biology; Homeobox protein NANOG; Cell biology; Ectopic expression; Repressor; Transcription factor; Cancer research; microRNA; High-mobility group; Molecular biology; Induced pluripotent stem cell; Cell culture; Gene; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001010887,0.0002650349,0.0001759263,0.0001697518,0.00009223053,0.000214747,0.00009764061,0.0001497934,0.0008190458],"category_scores_gemma":[0.00006187205,0.00013098,0.0001863274,0.00009769817,0.0001424905,0.0001180869,0.0001728034,0.0002378388,0.0002537169],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001445041,"about_ca_system_score_gemma":0.0001165171,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001520066,"about_ca_topic_score_gemma":0.0003196312,"domain_scores_codex":[0.9999093,0.00001658311,0.000008786391,0.00001964451,0.00002614839,0.00001959426],"domain_scores_gemma":[0.9999491,0.000005366864,0.00001575911,0.00000428506,0.000003711252,0.00002183455],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003027705,0.00000617115,0.000149352,0.000009356753,0.00000146669,0.0000210842,0.000004526823,0.00001040528,0.9993339,0.00005986029,0.00001300989,0.00036054],"study_design_scores_gemma":[0.00001284296,0.0001670565,0.006815359,0.000002758176,0.00001054483,0.0001507964,0.00001841926,0.0005376267,0.9907453,0.00004399618,0.001492519,0.00000283155],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9949278,0.001364676,0.001631163,0.00004681391,0.00001900109,0.00001602681,0.0001672201,0.00007422456,0.001753053],"genre_scores_gemma":[0.9963415,0.0005012315,0.0008536329,0.00003675332,0.000005827155,0.00002479517,0.0002852493,0.00001238593,0.001938492],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008190458,"threshold_uncertainty_score":0.002740026,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02313265525839015,"score_gpt":0.2505506020686138,"score_spread":0.2274179468102237,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}