{"id":"W2748117831","doi":"10.1038/s41598-017-09835-5","title":"Light-independent phospholipid scramblase activity of bacteriorhodopsin from Halobacterium salinarum","year":2017,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Photoreceptor and optogenetics research","field":"Neuroscience","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada Research Chairs; University of Toronto","funders":"National Institute of Neurological Disorders and Stroke; National Eye Institute; National Institutes of Health; University of Toronto; Office of Science; Velux Stiftung; Austrian Science Fund; National Energy Research Scientific Computing Center; Weill Cornell Medical College; Canada Excellence Research Chairs, Government of Canada; U.S. Department of Energy","keywords":"Halobacterium salinarum; Bacteriorhodopsin; Phospholipid scramblase; Transmembrane protein; Trimer; Transmembrane domain; Chemistry; Biochemistry; Phospholipid; Flippase; Vesicle; Biophysics; Lipid bilayer; Biology; Membrane; Phosphatidylserine; Dimer","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006266602,0.0001751021,0.0001478479,0.00007596305,0.000105234,0.0002055244,0.0001474663,0.0001600395,0.0003349859],"category_scores_gemma":[0.0001542383,0.00007148701,0.0002048189,0.00006346933,0.0001241102,0.0001393087,0.0001799662,0.0002040412,0.0001096741],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002727968,"about_ca_system_score_gemma":0.0001816856,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00237818,"about_ca_topic_score_gemma":0.0019132,"domain_scores_codex":[0.9999644,0.000004146254,0.000003844336,0.000007129155,0.00001296811,0.000007598802],"domain_scores_gemma":[0.9999664,0.000005426628,0.000008699692,0.000006033679,0.000004556828,0.000008904385],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004075007,0.000006822976,0.0001771891,0.00002241802,0.000004824829,0.00002187492,0.00001348354,0.0001751062,0.9987622,0.00005317595,0.00001339906,0.0007086452],"study_design_scores_gemma":[0.00002146454,0.00010147,0.005417888,0.000004810443,0.0000140214,0.00009013961,0.00003815019,0.003811202,0.9894672,0.00008687071,0.0009379528,0.00000880116],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9985891,0.00028737,0.0006511801,0.00003597279,0.000004856795,0.000004515531,0.00009873504,0.00003290356,0.0002952306],"genre_scores_gemma":[0.9985037,0.000162331,0.000842495,0.00001090178,7.462963e-7,0.0000037552,0.0002193903,0.0000110758,0.00024571],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00237818,"threshold_uncertainty_score":0.004728675,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04854353300847222,"score_gpt":0.3190290365573057,"score_spread":0.2704855035488335,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}