{"id":"W2748117831","doi":"10.1038/s41598-017-09835-5","title":"Light-independent phospholipid scramblase activity of bacteriorhodopsin from Halobacterium salinarum","year":2017,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Photoreceptor and optogenetics research","field":"Neuroscience","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada Research Chairs; University of Toronto","funders":"National Institute of Neurological Disorders and Stroke; National Eye Institute; National Institutes of Health; University of Toronto; Office of Science; Velux Stiftung; Austrian Science Fund; National Energy Research Scientific Computing Center; Weill Cornell Medical College; Canada Excellence Research Chairs, Government of Canada; U.S. Department of Energy","keywords":"Halobacterium salinarum; Bacteriorhodopsin; Phospholipid scramblase; Transmembrane protein; Trimer; Transmembrane domain; Chemistry; Biochemistry; Phospholipid; Flippase; Vesicle; Biophysics; Lipid bilayer; Biology; Membrane; Phosphatidylserine; Dimer","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001225512,0.0002420859,0.0003697875,0.0001607352,0.001085622,0.0009982979,0.001028701,0.0001350654,0.0008450021],"category_scores_gemma":[0.001487914,0.0002189865,0.0001968027,0.0002057253,0.0005653481,0.0005721961,0.0007788718,0.0002638341,0.0001383434],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001164399,"about_ca_system_score_gemma":0.0003149554,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006107111,"about_ca_topic_score_gemma":0.0001181436,"domain_scores_codex":[0.995895,0.0001549601,0.0005230283,0.001433239,0.001372378,0.0006214255],"domain_scores_gemma":[0.9952826,0.00008316828,0.0007822902,0.00329797,0.0001995916,0.0003543467],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007357039,0.0002022533,0.007580451,0.0000146516,0.000006603717,0.0003879925,0.0001700608,0.000001755427,0.9871749,0.00000807598,0.001978935,0.002400744],"study_design_scores_gemma":[0.0002004371,0.00004614185,0.03134122,0.000038147,0.000009979872,0.00004974187,0.000009884304,0.00008998463,0.9442549,0.00107547,0.02266869,0.0002154312],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9826608,0.0000219108,0.00004085623,0.0002721451,0.01259958,0.0003748932,0.0001000943,0.00004976784,0.003879999],"genre_scores_gemma":[0.99615,0.00001362186,0.0001523198,0.00002069568,0.0001359254,0.00001883682,0.00001053025,0.00002830149,0.003469761],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04292003,"threshold_uncertainty_score":0.962661,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04854353300847222,"score_gpt":0.3190290365573057,"score_spread":0.2704855035488335,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}