{"id":"W2748411395","doi":"10.1128/iai.00338-17","title":"Listeria monocytogenes and Shigella flexneri Activate the NLRP1B Inflammasome","year":2017,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":61,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; Government of Canada","keywords":"Inflammasome; Shigella flexneri; Listeria monocytogenes; Biology; Microbiology; Shigella; Pyroptosis; Innate immune system; Listeriolysin O; Listeria; Intracellular parasite; Phagolysosome; Immune system; Inflammation; Immunology; Bacteria; Salmonella; Phagosome; Phagocytosis; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001491574,0.0005162317,0.0001688117,0.0002113896,0.00009054007,0.0002515978,0.000101839,0.0003158161,0.000993546],"category_scores_gemma":[0.00007679313,0.0001634787,0.0002814453,0.00007701314,0.0002228573,0.0001726219,0.0002640006,0.0003576553,0.0003271234],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002103936,"about_ca_system_score_gemma":0.0001136372,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001971172,"about_ca_topic_score_gemma":0.0001535186,"domain_scores_codex":[0.9998797,0.00002797181,0.0000141579,0.00002159504,0.00002622964,0.0000302622],"domain_scores_gemma":[0.9999254,0.000008429143,0.00002836124,0.000007591589,0.000005745611,0.00002448719],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0001255437,0.00001675619,0.0002502783,0.00001837883,0.000002912728,0.00006299035,0.000008876546,0.00002384557,0.9991643,0.00004841061,0.00001570323,0.0002620169],"study_design_scores_gemma":[0.00007175978,0.0005883173,0.01570719,0.00002159178,0.00001532965,0.001159293,0.00009031397,0.0008202915,0.9797463,0.0002684396,0.001504287,0.000007022268],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955831,0.001587847,0.00157539,0.0001583423,0.00002748417,0.00001275761,0.0001854616,0.00004376249,0.0008258093],"genre_scores_gemma":[0.9970222,0.0006029835,0.00103098,0.0000522257,0.000007038705,0.00002069511,0.0001936157,0.000007778241,0.001062516],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000993546,"threshold_uncertainty_score":0.003323734,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0188553738866672,"score_gpt":0.2772145196545857,"score_spread":0.2583591457679185,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}