{"id":"W2748411395","doi":"10.1128/iai.00338-17","title":"Listeria monocytogenes and Shigella flexneri Activate the NLRP1B Inflammasome","year":2017,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":61,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; Government of Canada","keywords":"Inflammasome; Shigella flexneri; Listeria monocytogenes; Biology; Microbiology; Shigella; Pyroptosis; Innate immune system; Listeriolysin O; Listeria; Intracellular parasite; Phagolysosome; Immune system; Inflammation; Immunology; Bacteria; Salmonella; Phagosome; Phagocytosis; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002027835,0.0001281334,0.00009755171,0.00002259885,0.001087559,0.0002065473,0.0001373858,0.0001067399,0.0000169922],"category_scores_gemma":[0.0000989013,0.0000971039,0.00004442103,0.00001964317,0.0002611384,0.00002212394,0.0002889902,0.0001204549,0.00000574534],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000004602357,"about_ca_system_score_gemma":0.00001890934,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004979689,"about_ca_topic_score_gemma":0.0001729271,"domain_scores_codex":[0.9994602,0.00007723403,0.0001183177,0.0001541239,0.00004376271,0.0001463894],"domain_scores_gemma":[0.9992774,0.000009018552,0.0001050154,0.0005286531,0.00004503575,0.00003492717],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0002095062,0.0000336123,0.08099487,0.0000245739,0.00009037995,7.980868e-7,0.0002755329,0.000004355406,0.8788956,0.0001743785,0.0002162297,0.03908015],"study_design_scores_gemma":[0.0006133662,0.0002233687,0.6075268,0.00001089968,0.00001871089,0.00002613841,0.0001487389,0.00002251312,0.24816,0.0001709606,0.1428797,0.000198851],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9948148,0.0005368991,0.0000444308,0.0002757045,0.0002262456,0.0001221135,0.000002968185,0.00001210069,0.003964696],"genre_scores_gemma":[0.9963132,0.002721196,0.00001154029,0.0001393315,0.0001015217,0.00001495179,0.00001836324,0.00001156717,0.0006683189],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6307356,"threshold_uncertainty_score":0.8364732,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0188553738866672,"score_gpt":0.2772145196545857,"score_spread":0.2583591457679185,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}