{"id":"W2749157570","doi":"10.1038/cdd.2017.135","title":"Tudor-domain protein PHF20L1 reads lysine methylated retinoblastoma tumour suppressor protein","year":2017,"lang":"en","type":"article","venue":"Cell Death and Differentiation","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Ontario Ministry of Research and Innovation; Cancer Prevention and Research Institute of Texas; Medical Research Council; National Institute of Diabetes and Digestive and Kidney Diseases; Biotechnology and Biological Sciences Research Council; Rosetrees Trust; National Institutes of Health; Cancer Research UK; Wellcome Trust; Genome Canada; GlaxoSmithKline; Pfizer; Eli Lilly and Company","keywords":"Retinoblastoma protein; E2F; Methylation; Suppressor; Cyclin-dependent kinase; Phosphorylation; Lysine; Biology; Methyltransferase; Retinoblastoma; E2F1; Cell biology; Chemistry; Cancer research; Gene; Cell cycle; Biochemistry; Amino acid","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002351865,0.0002191791,0.0001871203,0.00005555627,0.0003872904,0.0001918369,0.0001893371,0.0002138594,0.00003468938],"category_scores_gemma":[0.0001422129,0.0002024125,0.00007434884,0.00003127352,0.0000577838,0.00001549135,0.0001421774,0.0001011578,0.000008665806],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001183865,"about_ca_system_score_gemma":0.00002996266,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004168889,"about_ca_topic_score_gemma":0.00002530917,"domain_scores_codex":[0.9987416,0.0001131466,0.0002568974,0.0004521314,0.0001718937,0.0002643154],"domain_scores_gemma":[0.9989178,0.000006726117,0.0002884026,0.0005258149,0.0001325317,0.0001287809],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000105609,0.00007543391,0.004933603,0.00005021959,0.00002038494,0.000001778654,0.00003560367,0.000002269422,0.9932311,0.0001659377,0.00002810017,0.001349971],"study_design_scores_gemma":[0.0009464342,0.0002290309,0.09604686,0.00002882153,0.00002896109,8.122611e-7,0.00001165666,0.0003549791,0.8995827,0.001719104,0.0008206905,0.0002299391],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9923777,0.00054884,0.004244105,0.0001352746,0.00008113623,0.0005859793,0.00001966086,0.0000202869,0.001987013],"genre_scores_gemma":[0.9959561,0.00008564467,0.001563369,0.0000124182,0.0001898115,0.00007507679,0.0003211343,0.00003017413,0.001766297],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09364837,"threshold_uncertainty_score":0.8254141,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01156379343298151,"score_gpt":0.2429618386227987,"score_spread":0.2313980451898172,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}