{"id":"W2749157570","doi":"10.1038/cdd.2017.135","title":"Tudor-domain protein PHF20L1 reads lysine methylated retinoblastoma tumour suppressor protein","year":2017,"lang":"en","type":"article","venue":"Cell Death and Differentiation","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Ontario Ministry of Research and Innovation; Cancer Prevention and Research Institute of Texas; Medical Research Council; National Institute of Diabetes and Digestive and Kidney Diseases; Biotechnology and Biological Sciences Research Council; Rosetrees Trust; National Institutes of Health; Cancer Research UK; Wellcome Trust; Genome Canada; GlaxoSmithKline; Pfizer; Eli Lilly and Company","keywords":"Retinoblastoma protein; E2F; Methylation; Suppressor; Cyclin-dependent kinase; Phosphorylation; Lysine; Biology; Methyltransferase; Retinoblastoma; E2F1; Cell biology; Chemistry; Cancer research; Gene; Cell cycle; Biochemistry; Amino acid","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009423364,0.0002890707,0.0002019389,0.0002036043,0.0003709714,0.000290134,0.0003531005,0.0003224636,0.003866492],"category_scores_gemma":[0.000158762,0.0001128599,0.0002233418,0.0001479502,0.0002134664,0.0002893225,0.0005967999,0.0003352507,0.001604295],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008299727,"about_ca_system_score_gemma":0.0002036684,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00184504,"about_ca_topic_score_gemma":0.002531245,"domain_scores_codex":[0.9998639,0.00000887157,0.000004396741,0.00005537154,0.00003244569,0.00003503996],"domain_scores_gemma":[0.9999299,0.000005426348,0.00002149706,0.000008546765,0.000007260452,0.0000274171],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001086906,0.00001088784,0.001020486,0.00004308362,0.000006909675,0.0001533652,0.00001544502,0.00005992366,0.9946657,0.0003320668,0.0002953185,0.003288127],"study_design_scores_gemma":[0.00001576179,0.0000898083,0.01874995,0.000008695488,0.00001333505,0.0008164329,0.00006079806,0.001710549,0.9602224,0.0001751516,0.01812878,0.000008265575],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9747593,0.004539653,0.009797209,0.000411291,0.0001083602,0.00003950201,0.001294437,0.0006205966,0.00842958],"genre_scores_gemma":[0.9829791,0.0004650729,0.001625599,0.00009773116,0.00001386737,0.00001329845,0.001228084,0.00004912938,0.0135281],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003866492,"threshold_uncertainty_score":0.01293468,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01156379343298151,"score_gpt":0.2429618386227987,"score_spread":0.2313980451898172,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}