{"id":"W2749710160","doi":"10.1016/j.biomaterials.2017.08.019","title":"The role of insulin growth factor-1 on the vascular regenerative effect of MAA coated disks and macrophage-endothelial cell crosstalk","year":2017,"lang":"en","type":"article","venue":"Biomaterials","topic":"Connective tissue disorders research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":42,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"Government of Shandong Province; Department of Family and Community Medicine, University of Toronto; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; University of Toronto; Canada Excellence Research Chairs, Government of Canada; Ontario Neurotrauma Foundation; Orthopaedic Research Foundation","keywords":"Macrophage polarization; Cell biology; M2 Macrophage; Growth factor; Crosstalk; Vascular endothelial growth factor; Angiogenesis; Macrophage; Chemistry; In vitro; Biology; Cancer research; Biochemistry; Receptor; VEGF receptors","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002867756,0.0003715692,0.0002057308,0.0002206602,0.0002638763,0.0005543501,0.0002180235,0.000438805,0.00148874],"category_scores_gemma":[0.0002831854,0.0001483737,0.0002458732,0.0001286906,0.0004182144,0.000609524,0.0002444166,0.0005317755,0.0001954455],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002706486,"about_ca_system_score_gemma":0.0003005247,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004521902,"about_ca_topic_score_gemma":0.0005075899,"domain_scores_codex":[0.9998022,0.00004878179,0.00001577207,0.00003018923,0.0000397489,0.00006338748],"domain_scores_gemma":[0.9998172,0.00007176627,0.00003206756,0.00001957579,0.00002713266,0.00003227832],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004468562,0.00003724059,0.0003241635,0.00007178989,0.000006432183,0.00009644857,0.0000367662,0.00004783606,0.9961929,0.0002602272,0.00003395198,0.002445365],"study_design_scores_gemma":[0.00003045994,0.0003961672,0.01281226,0.00002070345,0.00004349782,0.0002403978,0.0002605237,0.0007459193,0.9830632,0.0002820099,0.002094285,0.00001053972],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9877328,0.007844145,0.001722008,0.0002870972,0.00008315211,0.00001308258,0.0001236628,0.00002299263,0.002171138],"genre_scores_gemma":[0.9967912,0.001289065,0.0006981905,0.00005969375,0.00001739463,0.00001887635,0.00005290541,0.000005317919,0.001067413],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00148874,"threshold_uncertainty_score":0.004980326,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01032752051977309,"score_gpt":0.2799282405496778,"score_spread":0.2696007200299047,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}