{"id":"W2749857805","doi":"10.1152/ajpcell.00106.2017","title":"Molecular insights into the normal operation, regulation, and multisystemic roles of K+-Cl− cotransporter 3 (KCC3)","year":2017,"lang":"en","type":"review","venue":"American Journal of Physiology-Cell Physiology","topic":"Ion Transport and Channel Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Université Laval","funders":"","keywords":"Cotransporter; Gene isoform; Ouabain; Chemistry; Biology; Genetics; Gene; Sodium","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001961125,0.0005961043,0.0002708293,0.0004066262,0.0003011025,0.00069521,0.0005249243,0.0007066473,0.001005964],"category_scores_gemma":[0.0001017058,0.0001698641,0.0003193762,0.0002446523,0.0006481332,0.000691356,0.000235694,0.001366974,0.0004713075],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001290012,"about_ca_system_score_gemma":0.001107882,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.008403714,"about_ca_topic_score_gemma":0.008047092,"domain_scores_codex":[0.9999017,0.000006100933,0.000007111081,0.00002293944,0.00003394805,0.00002817489],"domain_scores_gemma":[0.9998959,0.000008739408,0.00002392289,0.000006345716,0.00003122014,0.00003382931],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002864353,0.00003475464,0.001264052,0.0002673259,0.0000105855,0.0008776495,0.00006235648,0.0003005878,0.9842948,0.002070199,0.0005500608,0.009981208],"study_design_scores_gemma":[0.0001037404,0.0008545695,0.0911831,0.000216024,0.0001893564,0.007497755,0.0007881314,0.008566936,0.7682283,0.005442885,0.1167949,0.0001342662],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.8077081,0.1548535,0.01970097,0.005840419,0.0004677344,0.00008898643,0.002061547,0.0005445956,0.00873413],"genre_scores_gemma":[0.9182988,0.05910828,0.01169104,0.00125745,0.0001793807,0.00003986099,0.001744228,0.00003602768,0.007644942],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.008403714,"threshold_uncertainty_score":0.01670963,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01044006913156752,"score_gpt":0.2558696358287918,"score_spread":0.2454295666972243,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}