{"id":"W2749858941","doi":"10.1002/1878-0261.12132","title":"Rho<scp>GDI</scp>β promotes Sp1/<scp>MMP</scp>‐2 expression and bladder cancer invasion through perturbing miR‐200c‐targeted <scp>JNK</scp>2 protein translation","year":2017,"lang":"en","type":"article","venue":"Molecular Oncology","topic":"Bladder and Urothelial Cancer Treatments","field":"Medicine","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Environmental Health Sciences; National Cancer Institute; School of Medicine, New York University; National Institutes of Health; National Natural Science Foundation of China; York University; University of Alabama; University of Alabama at Birmingham","keywords":"Protein expression; Translation (biology); Matrix metalloproteinase; microRNA; Cell biology; Biology; Cancer research; Chemistry; Messenger RNA; Biochemistry; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001407232,0.0003856678,0.0002539667,0.0002219437,0.0001712669,0.0002548212,0.0001161574,0.0001770783,0.0009663007],"category_scores_gemma":[0.00008201711,0.0001443677,0.0003639534,0.0001291315,0.0002383748,0.0001278334,0.0001749571,0.0006791011,0.00041194],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003086946,"about_ca_system_score_gemma":0.0003403544,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008677556,"about_ca_topic_score_gemma":0.001269233,"domain_scores_codex":[0.9998776,0.00001951101,0.00001315442,0.00001907484,0.00004020951,0.00003054087],"domain_scores_gemma":[0.9999449,0.000006013513,0.00001957781,0.00000616619,0.000007708128,0.00001561388],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006772542,0.00002283786,0.0001102369,0.00005204498,0.000005221876,0.00002967912,0.0000115208,0.00003666823,0.9988193,0.00005140892,0.00005766048,0.0007356554],"study_design_scores_gemma":[0.00002053185,0.0001723566,0.004019253,0.000006232097,0.0000161008,0.0002065445,0.00002286025,0.001075695,0.9915978,0.00003765443,0.002820515,0.000004408346],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9904907,0.002205224,0.003660522,0.0002194894,0.00004369388,0.00006683,0.0005442313,0.0001977292,0.00257155],"genre_scores_gemma":[0.992592,0.001345159,0.002627986,0.0001033413,0.00001151928,0.0000920401,0.0008588945,0.00004044899,0.002328782],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009663007,"threshold_uncertainty_score":0.003232658,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03839770651844352,"score_gpt":0.3233139216660085,"score_spread":0.2849162151475649,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}