{"id":"W2749899190","doi":"10.1016/b978-0-12-407691-4.00004-6","title":"Carvedilol","year":2013,"lang":"en","type":"review","venue":"Profiles of drug substances, excipients, and related methodology","topic":"Analytical Methods in Pharmaceuticals","field":"Chemistry","cited_by":38,"is_retracted":false,"has_abstract":false,"ca_institutions":"Apotex (Canada)","funders":"","keywords":"Carvedilol; Drug; ADME; Pharmacology; Stable angina; Heart failure; Medicine; Chemistry; Cardiology; Coronary heart disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003657558,0.0006915712,0.0005349852,0.001886862,0.0002049891,0.0004934542,0.0005334177,0.000499091,0.003757684],"category_scores_gemma":[0.0003173251,0.0001898175,0.0003344278,0.0007746344,0.0002453985,0.0003806469,0.0004049286,0.0008873111,0.002410549],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004630584,"about_ca_system_score_gemma":0.0007825091,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009280956,"about_ca_topic_score_gemma":0.002132383,"domain_scores_codex":[0.9997376,0.00003449363,0.00002196676,0.00004511923,0.0001315737,0.00002937477],"domain_scores_gemma":[0.9998657,0.00002734674,0.00002877147,0.000006361428,0.00005804364,0.00001390812],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003942296,0.0001412801,0.0004030518,0.00424244,0.00006133138,0.0002526446,0.00004123378,0.0001942781,0.08012693,0.002157386,0.007495875,0.9044893],"study_design_scores_gemma":[0.00008590775,0.001086778,0.004266351,0.001095516,0.0002666853,0.004601833,0.00007808729,0.0005868641,0.22138,0.001090205,0.765417,0.00004478906],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.02229846,0.9319862,0.0114728,0.001137104,0.0004485627,0.0002508632,0.001037312,0.0002604275,0.03110831],"genre_scores_gemma":[0.1258314,0.8185724,0.009340787,0.001525135,0.0002904649,0.0002265366,0.00183008,0.00004051662,0.04234258],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003757684,"threshold_uncertainty_score":0,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1978676490204516,"score_gpt":0.4344798437248264,"score_spread":0.2366121947043748,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}