{"id":"W2750063845","doi":"10.1016/j.bbapap.2017.08.007","title":"Recent advances in biophysical studies of rhodopsins – Oligomerization, folding, and structure","year":2017,"lang":"en","type":"review","venue":"Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics","topic":"Photoreceptor and optogenetics research","field":"Neuroscience","cited_by":34,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; University of Guelph","funders":"Canada Excellence Research Chairs, Government of Canada; Natural Sciences and Engineering Research Council of Canada; Canadian Institute for Advanced Research","keywords":"Bacteriorhodopsin; Rhodopsin; Biophysics; Folding (DSP implementation); Structural biology; Channelrhodopsin; Protein folding; Biology; Protein structure; Chemistry; Biochemistry; Computational biology; Retinal; Membrane; Neuroscience; Optogenetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009619096,0.0008029442,0.001013718,0.001286529,0.0002160843,0.0008443137,0.0008150436,0.0008203803,0.001760943],"category_scores_gemma":[0.001114051,0.0002626114,0.0003371292,0.001495043,0.0006344725,0.001621015,0.0009890595,0.001559605,0.001256369],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006505524,"about_ca_system_score_gemma":0.001128083,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000914435,"about_ca_topic_score_gemma":0.001590395,"domain_scores_codex":[0.9998198,0.00002200224,0.00002626108,0.00004341016,0.00006560123,0.00002303929],"domain_scores_gemma":[0.999398,0.0002769977,0.00007774875,0.00002541849,0.0001658706,0.00005591217],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001120882,0.00006036425,0.0003478838,0.01565112,0.00009170976,0.0001566249,0.00008108207,0.0004662849,0.01000858,0.005402043,0.02052966,0.9470927],"study_design_scores_gemma":[0.00001223863,0.00007407412,0.001358045,0.001930294,0.0001561672,0.0007793533,0.00009413027,0.0001559837,0.00427117,0.004549966,0.9865814,0.00003727758],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001892582,0.9984542,0.0002916746,0.0002689681,0.0001584252,0.000002594561,0.00001635528,0.000007072712,0.0006114365],"genre_scores_gemma":[0.0009132488,0.9978714,0.0003300985,0.0002141418,0.0002669703,0.000003289521,0.00004311531,0.000001703318,0.0003559168],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001760943,"threshold_uncertainty_score":0.005890906,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1482134910118771,"score_gpt":0.4261129574979529,"score_spread":0.2778994664860758,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}