{"id":"W2750674980","doi":"10.1038/s41598-017-11344-4","title":"Deamination-independent restriction of LINE-1 retrotransposition by APOBEC3H","year":2017,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Chromosomal and Genetic Variations","field":"Agricultural and Biological Sciences","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Retrotransposon; Deamination; Cytosine; Reverse transcriptase; Complementary DNA; ADAR; Biology; APOBEC3G; Genetics; DNA; RNA; Molecular biology; Enzyme; Cytidine deaminase; Biochemistry; RNA editing; Gene; Genome","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000121424,0.0001916408,0.0001412448,0.0001465191,0.0001105236,0.0001921606,0.000156709,0.0002030441,0.0009986835],"category_scores_gemma":[0.0002382201,0.00008365152,0.0002063701,0.00009366227,0.0001194545,0.0001131995,0.0001345177,0.0003225521,0.0002699255],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000168003,"about_ca_system_score_gemma":0.0001426466,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001002743,"about_ca_topic_score_gemma":0.001330824,"domain_scores_codex":[0.9998505,0.00003736716,0.00001184321,0.00003563091,0.00003356305,0.00003100823],"domain_scores_gemma":[0.9997694,0.00006366961,0.00006568613,0.00003493188,0.00003192859,0.00003441495],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003269121,0.000008399048,0.0007431453,0.00000781124,0.000003821915,0.00003066829,0.000006341706,0.00001527792,0.9983335,0.00002832936,0.000008106495,0.0007818753],"study_design_scores_gemma":[0.00001099613,0.000288078,0.03433966,0.000003882366,0.00001461218,0.0005748806,0.00002753665,0.0008574464,0.9627172,0.00006082183,0.001099174,0.000005640993],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9952527,0.0008232255,0.002705359,0.00002029331,0.00001032365,0.00001375313,0.0001050372,0.00002388911,0.001045384],"genre_scores_gemma":[0.9980227,0.0001764344,0.0009377529,0.00001587987,0.000003192079,0.000007296158,0.0001416092,0.000006871685,0.0006882675],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001002743,"threshold_uncertainty_score":0.0033409,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01557693088537606,"score_gpt":0.2318487465465792,"score_spread":0.2162718156612031,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}