{"id":"W2750674980","doi":"10.1038/s41598-017-11344-4","title":"Deamination-independent restriction of LINE-1 retrotransposition by APOBEC3H","year":2017,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Chromosomal and Genetic Variations","field":"Agricultural and Biological Sciences","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Retrotransposon; Deamination; Cytosine; Reverse transcriptase; Complementary DNA; ADAR; Biology; APOBEC3G; Genetics; DNA; RNA; Molecular biology; Enzyme; Cytidine deaminase; Biochemistry; RNA editing; Gene; Genome","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004338321,0.0000664084,0.00008683795,0.00001318963,0.0008730845,0.0002107594,0.0001601183,0.00006278883,0.0002121083],"category_scores_gemma":[0.00009686987,0.00002963213,0.00006844821,0.0001275581,0.0001041142,0.000170709,0.00003300426,0.00004680579,0.000008701177],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001839768,"about_ca_system_score_gemma":0.00001373721,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002952956,"about_ca_topic_score_gemma":0.0003803871,"domain_scores_codex":[0.9988847,0.00002183718,0.0002769439,0.0003320038,0.0003593144,0.000125224],"domain_scores_gemma":[0.9991782,0.0000203883,0.0003723081,0.0002073916,0.0001638039,0.00005789435],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.000003364107,0.00008123331,0.01524791,0.000003420036,0.000004601363,0.000008001498,0.00003093068,0.000008069672,0.9687155,0.000112101,0.001310356,0.0144745],"study_design_scores_gemma":[0.0001155794,0.0001689491,0.582059,0.00003820074,0.0000307421,0.00004345277,0.00005593783,0.0001758685,0.3707799,0.01468287,0.03164875,0.0002007597],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9952703,0.00003733281,0.00004791244,0.0006502782,0.001797363,0.0001534598,0.00002590397,0.00002322707,0.001994184],"genre_scores_gemma":[0.9983247,0.00001237542,0.00007312832,0.000005521627,0.00009008693,0.000009165593,0.0002125096,4.81776e-7,0.001272012],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5979356,"threshold_uncertainty_score":0.6715148,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01557693088537606,"score_gpt":0.2318487465465792,"score_spread":0.2162718156612031,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}