{"id":"W2750687089","doi":"10.15252/embr.201643289","title":"UbcD1 regulates Hedgehog signaling by directly modulating Ci ubiquitination and processing","year":2017,"lang":"en","type":"article","venue":"EMBO Reports","topic":"Hedgehog Signaling Pathway Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Program of Shanghai Academic Research Leader; National Key Research and Development Program of China; Chinese Academy of Sciences; Institute of Genetics; National Natural Science Foundation of China","keywords":"Molecular cell biology; Excellence; Chinese academy of sciences; Center of excellence; China; Cell and molecular biology; Cell signaling; Biology; Cell biology; Signal transduction; Political science; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004927368,0.0001543207,0.0001823087,0.00003592077,0.0004265862,0.0001327888,0.00008634636,0.0001096981,0.000002935511],"category_scores_gemma":[0.0005924908,0.0001555588,0.00003626792,0.00003131101,0.0001001477,0.00001401973,0.0001466193,0.00007384986,5.603196e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001503469,"about_ca_system_score_gemma":0.00003947005,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004325953,"about_ca_topic_score_gemma":0.0000240433,"domain_scores_codex":[0.9988114,0.00002986683,0.000326445,0.000461513,0.0001343871,0.0002363394],"domain_scores_gemma":[0.9991279,0.00001074488,0.0003585544,0.0003579922,0.00009194946,0.00005292304],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000007715154,0.00002193858,0.04127435,0.00005400282,0.00001579086,0.00006806185,0.0001897949,0.00008606996,0.9445114,0.000003359354,0.0002597916,0.01350776],"study_design_scores_gemma":[0.0002570119,0.00005988471,0.02536634,0.000197887,0.00001556776,0.0001114445,0.0001256755,0.0006499211,0.9696938,0.0003634477,0.002831926,0.0003270351],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946058,0.002318135,0.0002750924,0.0001243471,0.00009842456,0.0001386862,0.000002673445,0.00002278776,0.002414022],"genre_scores_gemma":[0.9985442,0.0000364975,0.000602243,0.00004121666,0.0001615509,0.00001951715,0.00003459881,0.00002589784,0.0005343032],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0251825,"threshold_uncertainty_score":0.6343505,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01347390244048846,"score_gpt":0.2690597230651966,"score_spread":0.2555858206247081,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}