{"id":"W2750731085","doi":"10.3390/ijms18091913","title":"Melatonin and Hippo Pathway: Is There Existing Cross-Talk?","year":2017,"lang":"en","type":"article","venue":"International Journal of Molecular Sciences","topic":"Hippo pathway signaling and YAP/TAZ","field":"Biochemistry, Genetics and Molecular Biology","cited_by":180,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; Juravinski Cancer Centre","funders":"Aboca S.p.A. Società Agricola","keywords":"Melatonin; Signal transduction; Receptor; Biology; Cytosol; Cell biology; Hormone; Melatonin receptor; Suppressor; G protein-coupled receptor; Neuroscience; Cancer; Endocrinology; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004498059,0.0004426193,0.0009621741,0.0005831117,0.0005250185,0.001254906,0.0005026574,0.001063343,0.001804238],"category_scores_gemma":[0.000346176,0.0001823285,0.0004265893,0.0005161645,0.0008821625,0.00173351,0.0008175062,0.001164235,0.0003158727],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006475251,"about_ca_system_score_gemma":0.0006413962,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005148347,"about_ca_topic_score_gemma":0.001000556,"domain_scores_codex":[0.9997675,0.00004121445,0.00001988429,0.00005520154,0.00004842006,0.00006785517],"domain_scores_gemma":[0.9998205,0.00004937287,0.00005511699,0.000009262425,0.00003198871,0.00003382908],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.001799358,0.000321038,0.01547299,0.01814916,0.001169477,0.01170767,0.002274347,0.001165794,0.1550245,0.09405039,0.02322605,0.6756392],"study_design_scores_gemma":[0.0001861048,0.002027004,0.09788729,0.003636544,0.001436498,0.02295383,0.005076162,0.002614073,0.0562059,0.1074843,0.7001926,0.0002996634],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.02123341,0.9639369,0.002458614,0.007428328,0.0007820389,0.0000201924,0.0001003425,0.00005577976,0.003984326],"genre_scores_gemma":[0.1707543,0.8188002,0.00181704,0.002821298,0.002388013,0.00005278404,0.0001685469,0.00001542648,0.003182466],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.001804238,"threshold_uncertainty_score":0.006035745,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0312729326430714,"score_gpt":0.3386231982621843,"score_spread":0.3073502656191129,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}