{"id":"W2750767712","doi":"10.1155/2017/2403072","title":"Expression of C4.4A in an In Vitro Human Tissue-Engineered Skin Model","year":2017,"lang":"en","type":"article","venue":"BioMed Research International","topic":"Skin and Cellular Biology Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Canadian Institutes of Health Research; Dansk Kræftforsknings Fond; H. Lundbeck A/S; Lundbeckfonden; Ministério da Ciência, Tecnologia e Inovação; Danmarks Grundforskningsfond; National Research Foundation; Fondation des pompiers du Québec pour les grands brûlés; Fabrikant Einar Willumsens Mindelegat; Kræftens Bekæmpelse; Fonds de Recherche du Québec - Santé; Université Laval","keywords":"Stratum spinosum; Keratinocyte; Epidermis (zoology); Cell biology; Human skin; Epithelium; Wound healing; Skin equivalent; Stratified squamous epithelium; Biology; Cell; In vitro; Pathology; Stratum corneum; Anatomy; Immunology; Medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001158368,0.00009428299,0.0001246434,0.0004281844,0.0001048122,0.00004923111,0.001067216,0.0002064985,0.00005564267],"category_scores_gemma":[0.0003443551,0.00008785992,0.00003933452,0.00007998514,0.000330865,0.00001429473,0.0004870649,0.0002549197,0.000007164015],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004405261,"about_ca_system_score_gemma":0.00009776078,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001458521,"about_ca_topic_score_gemma":0.000123061,"domain_scores_codex":[0.9984618,0.0001669165,0.00023118,0.0003570953,0.0004353385,0.000347711],"domain_scores_gemma":[0.9990487,0.00001828762,0.00005626486,0.0005469412,0.0002360515,0.00009381331],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002771967,0.0002206253,0.002730009,0.000009898741,0.000008943091,0.00002531045,0.00005042888,0.00003958391,0.9942786,0.0001318752,0.0004154021,0.001812098],"study_design_scores_gemma":[0.0009365609,0.0001378791,0.009639439,0.00002612856,4.273031e-7,0.000004368457,0.00004752949,0.002883445,0.9847949,0.0003636019,0.001075213,0.00009056698],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971951,0.0001164917,0.0002002491,0.0002655448,0.0001245716,0.0001844712,0.00004308665,0.000003129964,0.001867384],"genre_scores_gemma":[0.9976033,0.00006799003,0.0005814172,0.000006330501,0.0001932834,0.00005146239,0.0004111668,0.0000143149,0.001070738],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009483789,"threshold_uncertainty_score":0.3582823,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07299160566559176,"score_gpt":0.4310612547811695,"score_spread":0.3580696491155777,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}