{"id":"W2750976484","doi":"10.1021/acs.jproteome.7b00430","title":"Primary Metabolism and Medium-Chain Fatty Acid Alterations Precede Long-Chain Fatty Acid Changes Impacting Neutral Lipid Metabolism in Response to an Anticancer Lysophosphatidylcholine Analogue in Yeast","year":2017,"lang":"en","type":"article","venue":"Journal of Proteome Research","topic":"Metabolomics and Mass Spectrometry Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Natural Sciences and Engineering Research Council of Canada; American Cancer Society","keywords":"Lysophosphatidylcholine; Biochemistry; Fatty acid; Fatty acid metabolism; Metabolism; Lipid metabolism; Lipidomics; Biology; Butyrate; Metabolic pathway; Metabolome; Diacylglycerol kinase; Inositol; Phospholipid; Chemistry; Phosphatidylcholine; Metabolite; Signal transduction; Membrane; Fermentation","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008246153,0.000323262,0.0003003299,0.0001251748,0.0001050995,0.0002793379,0.000138348,0.0002406539,0.0005493637],"category_scores_gemma":[0.00010707,0.0001098399,0.0002233299,0.000211515,0.0001460616,0.0001533666,0.0002365083,0.0004136242,0.0001632102],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002014681,"about_ca_system_score_gemma":0.0001853181,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00182724,"about_ca_topic_score_gemma":0.001950079,"domain_scores_codex":[0.9999092,0.000009792116,0.00001025502,0.00002571073,0.00002235219,0.00002262325],"domain_scores_gemma":[0.9998977,0.00001276784,0.00002833345,0.00001115425,0.00002456302,0.00002544876],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000257158,0.00001224108,0.0002239087,0.00001237223,0.000003366088,0.00004489471,0.0000153125,0.00004042349,0.9988675,0.00001187558,0.00001048994,0.0005004996],"study_design_scores_gemma":[0.000007023051,0.0004158973,0.01504401,0.000004917335,0.0000144414,0.00009035678,0.0001109748,0.000672788,0.9829404,0.00003040445,0.0006625833,0.000006311269],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964848,0.000953536,0.001062114,0.00007052662,0.00002007652,0.00001692736,0.0008229886,0.00003325287,0.0005358065],"genre_scores_gemma":[0.9957417,0.0006075552,0.001189671,0.00007498238,0.000004657172,0.00002502314,0.0008928442,0.00001361963,0.00145],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00182724,"threshold_uncertainty_score":0.003633201,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04627953162779826,"score_gpt":0.3690488694008031,"score_spread":0.3227693377730048,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}