{"id":"W2751104442","doi":"10.1021/acsami.7b11528","title":"Tuning Antibacterial Activity of Cyclodextrin-Attached Cationic Ammonium Surfactants by a Supramolecular Approach","year":2017,"lang":"en","type":"article","venue":"ACS Applied Materials & Interfaces","topic":"Antimicrobial agents and applications","field":"Chemistry","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Centre for Bioengineering and Biotechnology, University of Waterloo; China University of Petroleum, Beijing; National Natural Science Foundation of China","keywords":"Cationic polymerization; Molecule; Pulmonary surfactant; Supramolecular chemistry; Cyclodextrin; Ammonium bromide; Antibacterial activity; Hydrophobic effect; Ammonium; Cytotoxicity; Materials science; Combinatorial chemistry; Chemistry; Chemical engineering; Organic chemistry; Polymer chemistry; Bacteria; In vitro; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002037274,0.0003151493,0.0005202633,0.0000312032,0.0004303201,0.0004246206,0.000914649,0.0002151525,0.0005933064],"category_scores_gemma":[0.00002749826,0.0003043793,0.00003355872,0.00003881817,0.0002636569,0.0002095334,0.0004003498,0.0001366575,0.00004210441],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004372833,"about_ca_system_score_gemma":0.00004734243,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000515538,"about_ca_topic_score_gemma":0.000006754498,"domain_scores_codex":[0.9984169,0.00002296477,0.0004617104,0.0005289364,0.0001978688,0.0003716435],"domain_scores_gemma":[0.99804,0.00002776804,0.0007896519,0.001009676,0.00006671013,0.0000662112],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002207619,0.00023952,0.0001406639,0.000153032,0.00009588108,6.200748e-7,0.0001206902,0.000005327979,0.9976397,0.0003765717,0.0003849202,0.000622318],"study_design_scores_gemma":[0.0005881351,0.00001112789,0.000470502,0.00003893067,0.00005913816,0.00000306779,0.0000548745,0.000004049192,0.997986,0.0000720082,0.0004094039,0.0003027919],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9913417,0.00001981591,0.0002955301,0.00009642595,0.0001404481,0.0002450013,0.0005360035,0.00007788405,0.007247231],"genre_scores_gemma":[0.9986343,0.00004975131,0.0004176883,0.00001622168,0.0001102638,0.00006779952,0.0002056238,0.00005347909,0.0004449077],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007292605,"threshold_uncertainty_score":0.9999408,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01667872036520357,"score_gpt":0.2603020175594085,"score_spread":0.2436232971942049,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}