{"id":"W2751159249","doi":"10.1093/biolre/iox110","title":"Low-dose metronomic delivery of cyclophosphamide is less detrimental to granulosa cell viability, ovarian function, and fertility than maximum tolerated dose delivery in the mouse†","year":2017,"lang":"en","type":"article","venue":"Biology of Reproduction","topic":"Reproductive Biology and Fertility","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"","keywords":"Cyclophosphamide; Chemotherapy; Follicle; Biology; Ovary; Fertility preservation; Internal medicine; Endocrinology; Fertility; Andrology; Oncology; Medicine; Population","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003519487,0.0004071787,0.0003629219,0.0005179474,0.0001958113,0.0004339592,0.0003298573,0.000513197,0.002107092],"category_scores_gemma":[0.0001740039,0.0002391919,0.0003090562,0.000198069,0.0004721961,0.0003923686,0.000153144,0.001042395,0.0002705104],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004550851,"about_ca_system_score_gemma":0.0004003948,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005766703,"about_ca_topic_score_gemma":0.001130219,"domain_scores_codex":[0.9997378,0.0000501239,0.00002809959,0.00006208187,0.00006592793,0.00005599779],"domain_scores_gemma":[0.9997414,0.00003942552,0.00009932977,0.00003789552,0.00001500442,0.00006702715],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008383262,0.0002250829,0.0003211934,0.00007074454,0.000008145235,0.00003638815,0.00002210767,0.0001383368,0.9947737,0.0002930957,0.0001304911,0.00314248],"study_design_scores_gemma":[0.0001219722,0.003732409,0.002594772,0.00001642566,0.00002603132,0.0001957628,0.00003564557,0.001014398,0.9885464,0.00009849101,0.003608351,0.000009315435],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.988555,0.002542057,0.004965388,0.0004194462,0.0001271484,0.0001143078,0.0008089838,0.0002415507,0.002226083],"genre_scores_gemma":[0.9888649,0.001110687,0.005407343,0.0001651501,0.0000325557,0.000164429,0.0004837005,0.00004772088,0.003723563],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002107092,"threshold_uncertainty_score":0.007048905,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02416933328701575,"score_gpt":0.2684844981098628,"score_spread":0.244315164822847,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}