{"id":"W2751257824","doi":"10.2217/rme-2017-0031","title":"Opportunities and Challenges for the Cellular Immunotherapy Sector: A Global Landscape of Clinical Trials","year":2017,"lang":"en","type":"article","venue":"Regenerative Medicine","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Simon Fraser University; Université de Montréal; Hôpital Maisonneuve-Rosemont; University of Alberta; Genome Canada","funders":"Genome Alberta; Alberta Innovates - Health Solutions; University of Alberta; Stem Cell Network; Génome Québec; Canadian Institutes of Health Research; Genome Canada","keywords":"Clinical trial; Identification (biology); Business; Translational research; Immunotherapy; Medicine; Cancer; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.009092333,0.0001985911,0.001331904,0.00005201416,0.0002807998,0.0000233295,0.0002558915,0.0001359494,0.0009974545],"category_scores_gemma":[0.00336917,0.000100665,0.0002369393,0.00003646246,0.001192171,0.00005108701,0.00006030999,0.0001877365,0.000001041306],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002315256,"about_ca_system_score_gemma":0.0002072505,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008658368,"about_ca_topic_score_gemma":0.00005903169,"domain_scores_codex":[0.9975789,0.0005937172,0.0008504808,0.0003039378,0.0004360772,0.0002368777],"domain_scores_gemma":[0.995728,0.002332148,0.0005476699,0.0008702267,0.0003538996,0.0001680629],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.005994755,0.0002196054,0.006607455,0.0004184484,0.002109091,0.00004591844,0.002204395,8.322359e-7,0.09610108,0.01627028,0.008949528,0.8610786],"study_design_scores_gemma":[0.04558055,0.01103846,0.05536261,0.0009506813,0.001019095,0.0001051438,0.009358893,0.002442227,0.04533819,0.001794361,0.8265358,0.0004739676],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.3959976,0.3757064,0.002429823,0.197322,0.001730096,0.004581194,0.000163862,0.00005708814,0.02201192],"genre_scores_gemma":[0.7912734,0.1928426,0.0003399198,0.0005056266,0.004736209,0.0001559299,0.00003430933,0.00004128767,0.01007079],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8606046,"threshold_uncertainty_score":0.9999158,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.5894884327791456,"score_gpt":0.5097814868901752,"score_spread":0.07970694588897043,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}