{"id":"W2751303173","doi":"10.1111/imj.67_13578","title":"P67: LONG‐TERM MANAGEMENT OF MODERATE‐TO‐SEVERE ATOPIC DERMATITIS WITH DUPILUMAB AND CONCOMITANT TOPICAL CORTICOSTEROIDS: A 1‐YEAR RANDOMIZED, PLACEBO‐CONTROLLED PHASE 3 TRIAL (CHRONOS)","year":2017,"lang":"en","type":"article","venue":"Internal Medicine Journal","topic":"Dermatology and Skin Diseases","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"SKiN Health","funders":"","keywords":"Medicine; Eczema Area and Severity Index; Atopic dermatitis; Dupilumab; Placebo; Concomitant; Regimen; Internal medicine; Randomized controlled trial; Placebo-controlled study; Clinical endpoint; Adverse effect; Dermatology; Double blind; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001283476,0.001188799,0.001731639,0.000346923,0.0004813138,0.0009237996,0.0007340208,0.001499137,0.003506022],"category_scores_gemma":[0.0006684742,0.0005149291,0.00147735,0.0002936798,0.0008577401,0.000837202,0.0003230639,0.002624235,0.0006447026],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005964016,"about_ca_system_score_gemma":0.001035065,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009621567,"about_ca_topic_score_gemma":0.003181889,"domain_scores_codex":[0.9997175,0.0001087939,0.00001765328,0.00005324305,0.00003730942,0.00006549363],"domain_scores_gemma":[0.9996175,0.00006714799,0.00009379491,0.0000216541,0.00002635461,0.0001735524],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9305851,0.01352399,0.001165574,0.001495448,0.000893339,0.0001559895,0.0001123483,0.0003358711,0.01059084,0.0001832541,0.001903984,0.0390542],"study_design_scores_gemma":[0.8634195,0.1305696,0.003708136,0.00005752524,0.0002909295,0.0001340452,0.00002839554,0.0003343248,0.0005436855,0.00008197009,0.0008117164,0.00002004077],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9893342,0.005884114,0.0003961822,0.0003748281,0.0002903657,0.001760634,0.000536733,0.0001229854,0.001300064],"genre_scores_gemma":[0.9883555,0.00348039,0.001158028,0.001051982,0.0004156431,0.00248951,0.0008888215,0.00002017336,0.002139913],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003506022,"threshold_uncertainty_score":0.01172888,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01660365024919002,"score_gpt":0.3193064312026972,"score_spread":0.3027027809535072,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}