{"id":"W2751388081","doi":"10.1002/bab.1607","title":"An activity transition from NADH dehydrogenase to NADH oxidase during protein denaturation","year":2017,"lang":"en","type":"article","venue":"Biotechnology and Applied Biochemistry","topic":"Enzyme Catalysis and Immobilization","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"FPInnovations","funders":"Army Research Office; Research Corporation for Science Advancement","keywords":"Cofactor; Enzyme; Biochemistry; Dehydrogenase; NAD+ kinase; Chemistry; Diaphorase; Oxidase test; NADH dehydrogenase; Nicotinamide","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001808114,0.0002502774,0.0001856917,0.0001192162,0.0001491148,0.0002542805,0.000248438,0.000292235,0.000621566],"category_scores_gemma":[0.0002783609,0.0001337355,0.0001789258,0.0001065305,0.0003150186,0.0003806968,0.0002397035,0.0005458929,0.0001902027],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001907391,"about_ca_system_score_gemma":0.0001293628,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002777946,"about_ca_topic_score_gemma":0.0002220176,"domain_scores_codex":[0.9998642,0.00001399416,0.00001071129,0.00004455029,0.00003708102,0.00002940155],"domain_scores_gemma":[0.9998831,0.0000266824,0.00002402072,0.00001699891,0.00002848248,0.00002071984],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003866124,0.00000938843,0.0003292272,0.00002684598,0.000004370249,0.00008774708,0.00005063319,0.00002378432,0.9971642,0.000172676,0.00002537229,0.002067039],"study_design_scores_gemma":[0.000003025925,0.00006835359,0.00208141,0.000003794502,0.000005059555,0.0002436073,0.00003775888,0.0003975918,0.9957824,0.0001278858,0.001244955,0.000004164207],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9697953,0.002436691,0.02480626,0.0003082643,0.000120796,0.00004250984,0.0001359596,0.0001608821,0.002193291],"genre_scores_gemma":[0.995032,0.0003692432,0.002944476,0.00007890785,0.00001061637,0.00001352137,0.00007690352,0.00001454796,0.001459687],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000621566,"threshold_uncertainty_score":0.002079308,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004491615351266882,"score_gpt":0.2238118057373867,"score_spread":0.2193201903861198,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}