{"id":"W2751632674","doi":"10.1016/j.biopsych.2017.08.002","title":"Targeting the Microbiome for Mental Health: Hype or Hope?","year":2017,"lang":"en","type":"letter","venue":"Biological Psychiatry","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":false,"ca_institutions":"St. Joseph’s Healthcare Hamilton","funders":"","keywords":"Mood; Mental health; Anxiety; Gut–brain axis; Microbiome; Gut flora; Curiosity; Psychology; Prebiotic; Depression (economics); Medicine; Social defeat; Neuroscience; Psychiatry; Bioinformatics; Biology; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00267224,0.0006008287,0.001456261,0.0004138265,0.002175234,0.002522978,0.0011975,0.02364228,0.0069232],"category_scores_gemma":[0.01339817,0.0003068319,0.0006201193,0.0003018763,0.004148916,0.004485633,0.001896056,0.03555077,0.004132784],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001852992,"about_ca_system_score_gemma":0.0021637,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001413821,"about_ca_topic_score_gemma":0.002465766,"domain_scores_codex":[0.9986874,0.000569452,0.0001143346,0.0001479092,0.000331756,0.0001490966],"domain_scores_gemma":[0.9926519,0.004936107,0.0003650351,0.0002349823,0.0007166893,0.001095197],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002081085,0.0001186378,0.0009879591,0.000145259,0.00004538933,0.00212049,0.0001552536,0.0001013942,0.0005233413,0.01004868,0.944732,0.04081346],"study_design_scores_gemma":[0.0003883586,0.0001851878,0.001127609,0.0006067582,0.00005989471,0.003028386,0.0009255885,0.0006855773,0.0004946199,0.06468393,0.9277189,0.00009518606],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.0002207721,0.005395856,0.00007809651,0.9860179,0.007607966,0.000002345765,0.00001485198,0.00001338506,0.0006486567],"genre_scores_gemma":[0.007149029,0.009754051,0.0003509462,0.9100845,0.06890509,0.00002131889,0.00001914044,0.00002070357,0.003695185],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.02364228,"threshold_uncertainty_score":0.0231604,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04213369780470503,"score_gpt":0.324199979195088,"score_spread":0.282066281390383,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}