{"id":"W2751644231","doi":"10.3390/v9090252","title":"Analysis of Class I Major Histocompatibility Complex Gene Transcription in Human Tumors Caused by Human Papillomavirus Infection","year":2017,"lang":"en","type":"article","venue":"Viruses","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":46,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lawson Health Research Institute; Western University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Major histocompatibility complex; Biology; MHC class I; Antigen processing; Antigen presentation; Antigen; Gene; HPV infection; CD8; Beta-2 microglobulin; Transcription (linguistics); Cancer research; Interferon; Immunology; Cervical cancer; Immune system; Cancer; Genetics; T cell","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001153781,0.0001071651,0.0001391899,0.0004149606,0.0001323516,0.000265806,0.00006391393,0.0001463599,0.000939994],"category_scores_gemma":[0.0002548499,0.0001018307,0.0001444465,0.00042188,0.0001530365,0.00008375138,0.0001028334,0.0002126934,0.0002461005],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001663218,"about_ca_system_score_gemma":0.0001382483,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006656376,"about_ca_topic_score_gemma":0.0005931988,"domain_scores_codex":[0.999882,0.00001726451,0.000008100653,0.00003047263,0.00002761967,0.00003446751],"domain_scores_gemma":[0.9998591,0.00005014581,0.0000300719,0.0000165901,0.00002250565,0.00002164298],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004201409,0.00003694591,0.01589375,0.00004710367,0.00001676034,0.00006798258,0.00008257717,0.00006697572,0.9808669,0.00005908671,0.00006358944,0.002378284],"study_design_scores_gemma":[0.00003200714,0.001018493,0.4926863,0.00001935074,0.0000936803,0.001015229,0.0003647215,0.001312684,0.4984766,0.0001522566,0.004817496,0.00001129138],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976655,0.0005490502,0.0006164727,0.0000119968,0.000008369209,0.00001349292,0.0006781032,0.00001275283,0.0004443534],"genre_scores_gemma":[0.9965941,0.0005548825,0.0005618019,0.00002763427,0.000006930311,0.00003243555,0.001467507,0.00001067233,0.0007441216],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000939994,"threshold_uncertainty_score":0.003144622,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05150448631361979,"score_gpt":0.3216847749811876,"score_spread":0.2701802886675678,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}