{"id":"W2751834855","doi":"10.1002/cpt.860","title":"Safety and Ergogenic Properties of Combined Aminophylline and Ambrisentan in Hypoxia","year":2017,"lang":"en","type":"article","venue":"Clinical Pharmacology & Therapeutics","topic":"High Altitude and Hypoxia","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"National Center for Advancing Translational Sciences; Defense Advanced Research Projects Agency; National Institutes of Health; Office of Naval Research; Gilead Sciences","keywords":"Aminophylline; Ambrisentan; Medicine; Hypoxia (environmental); Placebo; Pharmacology; Anesthesia; Internal medicine; Endothelin receptor; Bosentan; Oxygen; Chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003623176,0.0002309716,0.0005573292,0.000163735,0.0001763211,0.0001867179,0.0002391294,0.0003175902,0.0009862747],"category_scores_gemma":[0.0004036799,0.00009770357,0.0002011464,0.0000988395,0.0002394043,0.0002226589,0.0001236062,0.0003780082,0.0001548905],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001115554,"about_ca_system_score_gemma":0.0001976296,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002310053,"about_ca_topic_score_gemma":0.0005890875,"domain_scores_codex":[0.9997364,0.0001319121,0.00001866045,0.00002960967,0.00006390274,0.00001955604],"domain_scores_gemma":[0.9997928,0.00005038802,0.00006286033,0.00002394493,0.00002221718,0.00004794491],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.07987787,0.003628796,0.00817533,0.000524372,0.0004295124,0.0005713715,0.0001271557,0.0006623539,0.8012578,0.0002127263,0.0002818687,0.1042509],"study_design_scores_gemma":[0.01396169,0.470244,0.1226981,0.0001323399,0.001152191,0.003892445,0.0002707969,0.00381149,0.3750524,0.0002746425,0.008469829,0.00004018824],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995837,0.002564911,0.0006719728,0.00008330429,0.00002552494,0.00005973126,0.00005736121,0.00001989517,0.000680331],"genre_scores_gemma":[0.9983713,0.0006074618,0.0005197435,0.00005079911,0.00005272845,0.00003709931,0.00005055611,0.000002995835,0.0003073144],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009862747,"threshold_uncertainty_score":0.003299415,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05968574799120665,"score_gpt":0.3645254901035619,"score_spread":0.3048397421123553,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}