{"id":"W2752307697","doi":"10.1667/rr14911.1","title":"The CGL1 (HeLa × Normal Skin Fibroblast) Human Hybrid Cell Line: A History of Ionizing Radiation Induced Effects on Neoplastic Transformation and Novel Future Directions in SNOLAB","year":2017,"lang":"en","type":"review","venue":"Radiation Research","topic":"Effects of Radiation Exposure","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"NOSM University; Bruce Power (Canada); Laurentian University","funders":"","keywords":"Neoplastic transformation; HeLa; Neoplastic cell; Carcinogen; Carcinogenesis; Ionizing radiation; Biology; Cell culture; Non-ionizing radiation; Fibroblast; Cell; Malignant transformation; Cancer research; Cell type; Alkaline phosphatase; Cell biology; Cancer; Biochemistry; Genetics; Irradiation; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001695714,0.00063002,0.0009099208,0.001360249,0.0005031545,0.001447311,0.000787568,0.0007801942,0.002538255],"category_scores_gemma":[0.0006061023,0.0003546703,0.0007174555,0.001261104,0.0009617305,0.001407025,0.0007230472,0.002097862,0.001645663],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001253627,"about_ca_system_score_gemma":0.0007288366,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001598335,"about_ca_topic_score_gemma":0.002755382,"domain_scores_codex":[0.9993167,0.0001937865,0.00005527725,0.0001151511,0.0002504617,0.00006865425],"domain_scores_gemma":[0.9994531,0.0001734744,0.00006827497,0.0000620733,0.0001795872,0.00006352831],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0006279345,0.0004919585,0.003100377,0.002541181,0.00009258607,0.0006082173,0.0004893951,0.0007015017,0.7810842,0.008923311,0.004893818,0.1964456],"study_design_scores_gemma":[0.00004319566,0.0019315,0.00572883,0.0006364498,0.0001697217,0.002633758,0.0003773017,0.001607738,0.6304762,0.002967795,0.3533118,0.0001157074],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.1435337,0.7635966,0.04986012,0.007017166,0.0008991322,0.0004482759,0.001576634,0.0008060099,0.03226227],"genre_scores_gemma":[0.3238251,0.5719845,0.06392226,0.003182444,0.0004709682,0.0004643617,0.004744605,0.0004490356,0.03095682],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9984016,"threshold_uncertainty_score":0.009095669,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07379284247515268,"score_gpt":0.3905565085052969,"score_spread":0.3167636660301443,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}