{"id":"W2752434883","doi":"10.1242/dev.149120","title":"The receptor protein tyrosine phosphatase PTPRB negatively regulates FGF2-dependent branching morphogenesis","year":2017,"lang":"en","type":"article","venue":"Development","topic":"Cancer Cells and Metastasis","field":"Medicine","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Cancer Research; Cardiff University; Cancer Research UK; Canolfan Ymchwil Canser Cymru; Breast Cancer Now","keywords":"Biology; Cell biology; Morphogenesis; Gene knockdown; Fibroblast growth factor; Organoid; Receptor tyrosine kinase; Angiogenesis; Endocrinology; Signal transduction; Internal medicine; Receptor; Cancer research; Cell culture; Biochemistry; Gene; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["sts"],"consensus_categories":[],"category_scores_codex":[0.0005685349,0.0002258045,0.000287776,0.00004124381,0.001317657,0.0001975078,0.0003001746,0.00005648212,0.000283007],"category_scores_gemma":[0.0001858121,0.0001501783,0.00008368147,0.00006424783,0.0001230887,0.0001152284,0.0001855776,0.000148569,0.0001772912],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002142267,"about_ca_system_score_gemma":0.0003651998,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002140322,"about_ca_topic_score_gemma":0.0001248729,"domain_scores_codex":[0.9983985,0.00003104976,0.0003616877,0.0003651618,0.0004542302,0.0003893561],"domain_scores_gemma":[0.9986788,0.0000352395,0.0002625388,0.0007065201,0.0001247612,0.0001921419],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008368182,0.0002366991,0.003560973,0.0001793924,0.0004566722,0.00008291928,0.001264956,0.000005072773,0.1470213,0.0007258453,0.01104517,0.8345842],"study_design_scores_gemma":[0.001076465,0.00003803654,0.03103028,0.0001812431,0.00003451047,0.00001031429,0.00008670425,0.000004820392,0.6473666,0.00003227949,0.3199739,0.000164792],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9851078,0.004785919,0.0002969595,0.005616487,0.0007290556,0.001364945,0.00004244892,0.00008055357,0.001975804],"genre_scores_gemma":[0.9604818,0.0005165691,0.01691842,0.0003361908,0.0002533213,0.0003039938,0.00006445392,0.00005335101,0.02107188],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8344194,"threshold_uncertainty_score":0.9999825,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02348110601103324,"score_gpt":0.2701421109124281,"score_spread":0.2466610049013949,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}