{"id":"W2752530165","doi":"10.3747/co.24.3516","title":"Phase I/II Trial of Dose-Reduced Capecitabine in Elderly Patients with Advanced Colorectal Cancer","year":2017,"lang":"en","type":"article","venue":"Current Oncology","topic":"Colorectal Cancer Treatments and Studies","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"Burnaby Hospital; Cancer Care Ontario; Lions Gate Hospital; Queen's University; Ottawa Hospital; Western University","funders":"F. Hoffmann-La Roche; Roche","keywords":"Capecitabine; Medicine; Internal medicine; Toxicity; Colorectal cancer; Chemotherapy; Radiation therapy; Cohort; Gastroenterology; Cancer; Surgery; Oncology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002398518,0.001351084,0.001518554,0.000361588,0.0003802972,0.0006181228,0.0006812967,0.0008139558,0.003222637],"category_scores_gemma":[0.001361125,0.0004340119,0.0008586633,0.0004467331,0.0007630883,0.0004585611,0.0003749945,0.002623529,0.0005340447],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000969824,"about_ca_system_score_gemma":0.001543982,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001028749,"about_ca_topic_score_gemma":0.002328563,"domain_scores_codex":[0.9995533,0.000269528,0.00002643253,0.00006037082,0.00003095868,0.00005934668],"domain_scores_gemma":[0.9992136,0.0001583714,0.0001679134,0.0000647825,0.00005387895,0.0003413953],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.8799936,0.03138755,0.009535191,0.001034581,0.001162852,0.0003456419,0.0002676075,0.002233896,0.0212105,0.0001843763,0.004937342,0.04770688],"study_design_scores_gemma":[0.8372062,0.1481639,0.01013257,0.00003315276,0.0002827354,0.0001548889,0.000030848,0.0009994358,0.00113527,0.00008898255,0.001756731,0.00001521431],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9922621,0.001919763,0.0003934057,0.0006268451,0.0001668973,0.002718522,0.0006585288,0.00004302786,0.001210941],"genre_scores_gemma":[0.98881,0.001493956,0.00175796,0.001119605,0.0002601805,0.002980802,0.001842903,0.00001838795,0.001716316],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003222637,"threshold_uncertainty_score":0.01268476,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07071409868069715,"score_gpt":0.4287035269683336,"score_spread":0.3579894282876364,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}