{"id":"W2752651598","doi":"10.12688/f1000research.11976.1","title":"Protein clustering for cell polarity: Par-3 as a paradigm","year":2017,"lang":"en","type":"preprint","venue":"F1000Research","topic":"Cellular Mechanics and Interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Cell polarity; Centrosome; Caenorhabditis elegans; Scaffold protein; Microtubule; Cell biology; Biology; Cytoskeleton; Polarity (international relations); Phosphoproteomics; Phosphorylation; Cell; Neuroscience; Protein kinase A; Signal transduction; Protein phosphorylation; Genetics; Cell cycle; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005352239,0.0005969276,0.0006786624,0.0005327917,0.0007877602,0.00138856,0.0009402995,0.001700124,0.003735775],"category_scores_gemma":[0.0003799807,0.000229936,0.0004423542,0.0005853569,0.002734196,0.003550656,0.001177379,0.00266461,0.002422577],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00185937,"about_ca_system_score_gemma":0.0006543211,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005916776,"about_ca_topic_score_gemma":0.0007347801,"domain_scores_codex":[0.9997633,0.00005431736,0.0000109915,0.0000580035,0.00007525019,0.00003817198],"domain_scores_gemma":[0.9998795,0.00003926607,0.00001541514,0.0000138419,0.00002372644,0.00002827496],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001240061,0.00001786735,0.0002495671,0.001645264,0.00004474508,0.0005220692,0.0004996164,0.001519173,0.04500233,0.8164264,0.05842711,0.07552187],"study_design_scores_gemma":[0.00001589622,0.00005768505,0.0005939084,0.0002827371,0.00002216269,0.0008421863,0.0002951974,0.001265885,0.007576894,0.2193231,0.7696995,0.0000248559],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.01386505,0.7855222,0.05575758,0.06292549,0.007583877,0.00003348247,0.0002450894,0.0004560894,0.07361114],"genre_scores_gemma":[0.2364187,0.6628087,0.02100253,0.01995346,0.008413557,0.0001590376,0.0004441989,0.0003172519,0.05048257],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.003735775,"threshold_uncertainty_score":0.01349074,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04845636109747664,"score_gpt":0.3588059526864674,"score_spread":0.3103495915889907,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}