{"id":"W2752679333","doi":"10.1111/neup.12405","title":"Frequency of <i>MYD88</i> and <i>CD79B</i> mutations, and <i>MGMT</i> methylation in primary central nervous system diffuse large <scp>B</scp>‐cell lymphoma","year":2017,"lang":"en","type":"article","venue":"Neuropathology","topic":"CNS Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":47,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"National Cancer Institute; University of Nebraska Medical Center","keywords":"Diffuse large B-cell lymphoma; Cancer research; Lymphoma; Methylation; O-6-methylguanine-DNA methyltransferase; Mutation; Methyltransferase; Biology; Medicine; Internal medicine; Primary central nervous system lymphoma; Oncology; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002500339,0.0001612934,0.0002145939,0.000944166,0.0002315762,0.0004029899,0.0002295765,0.0005074353,0.001475795],"category_scores_gemma":[0.001125862,0.0002967805,0.000163472,0.0004235368,0.0005759065,0.0002572749,0.0002745557,0.000220828,0.000340473],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00021675,"about_ca_system_score_gemma":0.0001156023,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001565973,"about_ca_topic_score_gemma":0.001471887,"domain_scores_codex":[0.9996624,0.00005589838,0.00004397408,0.00009601132,0.00007368685,0.0000681123],"domain_scores_gemma":[0.9993974,0.0001626287,0.0002156461,0.00006141567,0.00005277001,0.0001101178],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0001240854,0.00001973804,0.9907289,0.00001064702,0.00002148891,0.000939465,0.0001541704,0.00005532677,0.00565438,0.00001735298,0.0001169815,0.002157634],"study_design_scores_gemma":[0.000009251106,0.00008489435,0.9914382,0.000003654411,0.00002389279,0.00664654,0.000173659,0.0001985142,0.001215809,0.00002215924,0.0001782721,0.000005302245],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9996731,0.00008310873,0.00003362087,0.0000100307,9.33184e-7,0.000001659516,0.0000342778,0.00000412223,0.0001591076],"genre_scores_gemma":[0.999792,0.0000383212,0.00003096649,0.000009983431,0.000004642284,0.000002412801,0.00005316016,0.000001677363,0.00006673006],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001565973,"threshold_uncertainty_score":0.004936993,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008828191879746147,"score_gpt":0.2319739042883163,"score_spread":0.2231457124085701,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}