{"id":"W2752679333","doi":"10.1111/neup.12405","title":"Frequency of <i>MYD88</i> and <i>CD79B</i> mutations, and <i>MGMT</i> methylation in primary central nervous system diffuse large <scp>B</scp>‐cell lymphoma","year":2017,"lang":"en","type":"article","venue":"Neuropathology","topic":"CNS Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":47,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"National Cancer Institute; University of Nebraska Medical Center","keywords":"Diffuse large B-cell lymphoma; Cancer research; Lymphoma; Methylation; O-6-methylguanine-DNA methyltransferase; Mutation; Methyltransferase; Biology; Medicine; Internal medicine; Primary central nervous system lymphoma; Oncology; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002196172,0.000232449,0.0005599512,0.000148874,0.0001740701,0.00003921257,0.0001052481,0.0001479117,0.000001294629],"category_scores_gemma":[0.0002370341,0.0002101791,0.00006921738,0.00007717754,0.0001992713,0.0001436771,0.0001258956,0.0001018763,0.000005951425],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009928017,"about_ca_system_score_gemma":0.00008687245,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001660861,"about_ca_topic_score_gemma":0.00006010565,"domain_scores_codex":[0.9983483,0.000182563,0.0004364492,0.0004684027,0.0001694468,0.0003948171],"domain_scores_gemma":[0.9986057,0.0002993035,0.0003257283,0.0005441151,0.00006246779,0.000162729],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00003341918,0.001642335,0.934237,0.0004485199,0.00002053499,0.002231493,0.0006391587,0.000001179725,0.04296684,0.0008470787,0.0001148112,0.01681764],"study_design_scores_gemma":[0.009154328,0.0003021448,0.9816117,0.00009804408,0.0001668526,0.001072661,0.0001440039,0.00008464983,0.006810858,0.00006901957,0.0004143722,0.00007138486],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9921284,0.002674357,0.00003473258,0.0001860527,0.0002349198,0.0005017851,0.00007487756,0.00004695432,0.004117963],"genre_scores_gemma":[0.9981004,0.0008094718,0.0004153978,0.0004006121,0.00006020173,0.00005058456,0.00005050038,0.00003649712,0.00007630735],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04737469,"threshold_uncertainty_score":0.8570855,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008828191879746147,"score_gpt":0.2319739042883163,"score_spread":0.2231457124085701,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}