{"id":"W2752699676","doi":"10.1007/s40262-017-0593-6","title":"Population Pharmacokinetics of Mycophenolic Acid: An Update","year":2017,"lang":"en","type":"review","venue":"Clinical Pharmacokinetics","topic":"Renal Transplantation Outcomes and Treatments","field":"Medicine","cited_by":46,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia; University of Alberta","funders":"","keywords":"Pharmacokinetics; Population; Pharmacology; Mycophenolic acid; Population pharmacokinetics; NONMEM; Medicine; Physiologically based pharmacokinetic modelling; Pharmacodynamics; Transplantation; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005086494,0.0006558396,0.003548795,0.0002401903,0.0001019773,0.00004298453,0.0005319283,0.0005246949,0.0004453074],"category_scores_gemma":[0.0001362385,0.0005014184,0.001315848,0.0001895491,0.0002141739,0.000118515,0.00008468614,0.0008780052,0.0001920443],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005869408,"about_ca_system_score_gemma":0.0002124683,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001303552,"about_ca_topic_score_gemma":0.000001185293,"domain_scores_codex":[0.9955107,0.0003363074,0.002543537,0.000700455,0.000519182,0.0003897935],"domain_scores_gemma":[0.9961364,0.0002851134,0.001710142,0.00110254,0.0002033648,0.0005624112],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001357551,0.000845157,0.001418169,0.01769028,0.001144393,0.0001537513,0.0000107447,0.000002281333,0.000004081272,0.00004291934,0.0002913172,0.9782612],"study_design_scores_gemma":[0.004187871,0.000537711,0.002116469,0.009327738,0.01501553,0.0001167863,0.000001251206,0.00008376619,0.0000321572,0.00005659042,0.9680728,0.0004513805],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0004480298,0.9946018,0.00006891832,0.00004906149,0.001623667,0.001430451,0.0004849461,0.00008536786,0.00120777],"genre_scores_gemma":[0.002720449,0.990742,0.001629775,0.0002645995,0.001062903,0.00003831983,0.002834971,0.0001391311,0.0005678909],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9778098,"threshold_uncertainty_score":0.9997438,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.3131514110980119,"score_gpt":0.5575333696247633,"score_spread":0.2443819585267514,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}