{"id":"W2752712572","doi":"10.1039/c7cc06299k","title":"Clustering of P<sup>K</sup>-trisaccharides on amphiphilic cyclodextrin reveals unprecedented affinity for the Shiga-like toxin Stx2","year":2017,"lang":"en","type":"article","venue":"Chemical Communications","topic":"Escherichia coli research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Glycomics Centre; Calgary Laboratory Services; Alberta Hospital Edmonton; University of Alberta; University of Calgary","funders":"Alberta Innovates - Technology Futures","keywords":"Shiga toxin; Cyclodextrin; Chemistry; Amphiphile; STX2; Cluster analysis; Stereochemistry; Combinatorial chemistry; Organic chemistry; Biochemistry; Escherichia coli; Copolymer; Polymer; Computer science","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007058607,0.0002911699,0.0001694691,0.00009339461,0.0001615575,0.0002886628,0.0001556858,0.0001913899,0.0004828831],"category_scores_gemma":[0.0001412413,0.0001319503,0.000107121,0.0001082007,0.0002036185,0.0001281094,0.0002204474,0.0002425037,0.0002515223],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002491546,"about_ca_system_score_gemma":0.0001299339,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004769055,"about_ca_topic_score_gemma":0.00082374,"domain_scores_codex":[0.9999052,0.00001189052,0.000003651029,0.00002734566,0.00001945197,0.00003234627],"domain_scores_gemma":[0.9999284,0.00001311841,0.00001502428,0.000009228806,0.00001308149,0.00002118022],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003051845,0.00000515872,0.0001005241,0.000006240581,0.000001956958,0.0000139154,0.000007664831,0.00007575169,0.9992391,0.00002697789,0.00002038808,0.0004719613],"study_design_scores_gemma":[0.000003445484,0.00008146839,0.003465329,0.000002230852,0.000005333422,0.00007986454,0.00002649542,0.001487545,0.9942766,0.00002499369,0.0005405887,0.000006152933],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996179,0.0001103851,0.002728826,0.00004217326,0.000006013602,0.00001344272,0.00007030027,0.00003968932,0.0008100939],"genre_scores_gemma":[0.9960619,0.0001354606,0.002444643,0.00006634739,0.00000253907,0.0000180382,0.0001246333,0.00001526026,0.001131194],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0004828831,"threshold_uncertainty_score":0.00180769,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07666113577849563,"score_gpt":0.36324815254602,"score_spread":0.2865870167675243,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}