{"id":"W2752906144","doi":"10.1039/c7cc05576e","title":"A mutation-resistant deoxyribozyme OR gate for highly selective detection of viral nucleic acids","year":2017,"lang":"en","type":"article","venue":"Chemical Communications","topic":"Viral Infections and Immunology Research","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Population and Public Health","funders":"National Institute of Allergy and Infectious Diseases; ITMO University; National Health Research Institutes; Ministry of Science and Technology, Taiwan; National Science Foundation","keywords":"Deoxyribozyme; Nucleic acid; Enterovirus; Virology; DNA; Biology; Mutation; Chemistry; Virus; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003298746,0.0003991159,0.0002453971,0.0001794291,0.000137275,0.0003116582,0.0003200837,0.000394798,0.0005930272],"category_scores_gemma":[0.0003241721,0.0001813003,0.0001759807,0.0001200126,0.000291274,0.0002833442,0.000307378,0.0004154399,0.0002603701],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002186351,"about_ca_system_score_gemma":0.0001850003,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008755534,"about_ca_topic_score_gemma":0.0001543737,"domain_scores_codex":[0.9997422,0.00005259164,0.00001926652,0.00007655206,0.00006676582,0.0000426202],"domain_scores_gemma":[0.999817,0.0000651158,0.00005499724,0.00001921896,0.00001828071,0.00002556322],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003487187,0.00001028248,0.00005846622,0.00004240802,0.00000405757,0.00005421627,0.00001633701,0.000122583,0.9958443,0.0007576824,0.00005424109,0.003000513],"study_design_scores_gemma":[0.000009486755,0.0001323543,0.0001466938,0.000003010131,0.0000069945,0.0002456915,0.00000489543,0.00125379,0.99554,0.00009651586,0.002553687,0.000006893604],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7748177,0.001504205,0.2143227,0.0002639685,0.0001834816,0.0002120943,0.0003168535,0.0008930143,0.007486021],"genre_scores_gemma":[0.9363338,0.0005196144,0.05970404,0.0002376313,0.00002619218,0.0001005068,0.0002147903,0.00006933202,0.002794111],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005930272,"threshold_uncertainty_score":0.001983881,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06637011778917691,"score_gpt":0.3820256374640055,"score_spread":0.3156555196748286,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}