{"id":"W2753546305","doi":"10.1101/142539","title":"HIV disrupts CD34 <sup>+</sup> progenitors involved in T-cell differentiation","year":2017,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Infection and Immunity; Medical Research Council; Center for AIDS Research, University of Washington; University of New South Wales; Ministry of Education, Culture, Sports, Science and Technology; National Health and Medical Research Council; Japan Agency for Medical Research and Development","keywords":"Haematopoiesis; CD34; Progenitor cell; Biology; Stem cell; CXCR4; Cell biology; Immunology; T cell; Virology; Immune system; Chemokine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001166117,0.0001910245,0.000114216,0.0001975716,0.0001582135,0.0003750186,0.0001771499,0.000212271,0.002273324],"category_scores_gemma":[0.00007696285,0.0001121674,0.0001072023,0.00009791753,0.0001716651,0.0001320558,0.0002412601,0.0005674514,0.0006811406],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001977135,"about_ca_system_score_gemma":0.0001664078,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005825287,"about_ca_topic_score_gemma":0.0006253396,"domain_scores_codex":[0.999899,0.00002176361,0.000008638211,0.00001240748,0.00002731593,0.0000309202],"domain_scores_gemma":[0.9999503,0.00001243705,0.000008937131,0.000008319271,0.000005436818,0.00001454963],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009948356,0.00002381652,0.0003643827,0.00001999018,0.000002656807,0.00007030364,0.00001394602,0.00005272293,0.9977852,0.000211401,0.00008632384,0.001269829],"study_design_scores_gemma":[0.000006130651,0.00006878223,0.003340169,0.000005689534,0.00000396917,0.0002457708,0.00002549318,0.0006329727,0.9927434,0.00007292965,0.002853343,0.000001366788],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9924381,0.001260625,0.00259268,0.0001115596,0.0000296403,0.00003390023,0.0007352237,0.00007989855,0.002718407],"genre_scores_gemma":[0.9897248,0.0005391556,0.00336377,0.00006066606,0.00001043188,0.00002608869,0.001177038,0.00003820782,0.005059876],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002273324,"threshold_uncertainty_score":0.007605016,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01673589564142563,"score_gpt":0.2378637058125968,"score_spread":0.2211278101711712,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}