{"id":"W2753599791","doi":"10.1093/ofid/ofx163.1393","title":"RBX2660 is Safe, Superior to Antibiotic-Treated Controls for Preventing Recurrent Clostridium difficile, and May Rehabilitate Patient Microbiomes: Open Label Trial Results","year":2017,"lang":"en","type":"article","venue":"Open Forum Infectious Diseases","topic":"Clostridium difficile and Clostridium perfringens research","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Medicine; Clostridium difficile; Adverse effect; Open label; Internal medicine; Antibiotics; Clinical trial; Surgery","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","sts","scholarly_communication"],"consensus_categories":[],"category_scores_codex":[0.000636536,0.000606856,0.001295979,0.0002743463,0.001735488,0.002277734,0.001128395,0.0002114966,0.0001507618],"category_scores_gemma":[0.00360563,0.0005234784,0.0002967602,0.0002896514,0.0002947033,0.0005692837,0.002626269,0.0002948743,0.00008407317],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003625803,"about_ca_system_score_gemma":0.0005385301,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001928603,"about_ca_topic_score_gemma":0.0003270674,"domain_scores_codex":[0.9956354,0.0001764725,0.001113915,0.00143313,0.0004625264,0.001178486],"domain_scores_gemma":[0.9957747,0.0005147558,0.0005039059,0.001709016,0.0005863269,0.0009112955],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.4324035,0.01893076,0.06461444,0.001364291,0.001931024,0.0002133534,0.001048076,0.000005758438,0.07452539,0.0003687452,0.2036154,0.2009793],"study_design_scores_gemma":[0.4985276,0.0586668,0.02325227,0.003581196,0.002080009,0.0001394198,0.001408127,0.0003309363,0.2178321,0.0003396768,0.1910932,0.002748595],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.961843,0.0004325983,0.000005335657,0.008394973,0.0005912847,0.01784571,0.004661308,0.0000829757,0.00614284],"genre_scores_gemma":[0.9940943,0.0002280115,0.0002476105,0.000634917,0.0002355914,0.0008966403,0.0004424824,0.0001079761,0.003112454],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1982307,"threshold_uncertainty_score":0.9997217,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04402170445540123,"score_gpt":0.3710759169329225,"score_spread":0.3270542124775213,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}