{"id":"W2753952998","doi":"10.1038/onc.2017.324","title":"ING5 activity in self-renewal of glioblastoma stem cells via calcium and follicle stimulating hormone pathways","year":2017,"lang":"en","type":"article","venue":"Oncogene","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research; Alberta Cancer Foundation; University of Calgary","keywords":"Biology; Stem cell; SOX2; H3K4me3; Histone acetyltransferase; Cancer research; Epigenetics; Cell biology; Transcription factor; Genetics; Gene expression; Promoter; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007885585,0.0001751547,0.00009505003,0.0001479834,0.0001102785,0.0001770145,0.00009152829,0.0001034057,0.0005682728],"category_scores_gemma":[0.00005414874,0.00006532595,0.0001537834,0.00009722113,0.00009627981,0.00008044331,0.0001370735,0.0001154886,0.0001304084],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003139596,"about_ca_system_score_gemma":0.0001825018,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001447891,"about_ca_topic_score_gemma":0.002663723,"domain_scores_codex":[0.9999558,0.000006972867,0.000003216738,0.000008823175,0.00001033621,0.00001484066],"domain_scores_gemma":[0.9999733,0.000002436157,0.0000093453,0.000002503009,0.000002625867,0.000009889797],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001591753,0.00001910167,0.001852395,0.00005296565,0.00001049787,0.00005844887,0.00001761783,0.00016975,0.9941627,0.0001766574,0.00007947371,0.003241178],"study_design_scores_gemma":[0.00001622333,0.0002137746,0.0411923,0.000009191705,0.00005314374,0.0001812457,0.00005205743,0.001855384,0.9518091,0.0001265049,0.004485169,0.000005994137],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9944382,0.002352643,0.001181627,0.0000597715,0.000009855156,0.000009435063,0.0002169202,0.00005820154,0.001673344],"genre_scores_gemma":[0.9981467,0.0004472343,0.0003883263,0.00002188699,0.000001760824,0.000004206885,0.0002288697,0.000002931503,0.0007581027],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001447891,"threshold_uncertainty_score":0.002878964,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02092032481733045,"score_gpt":0.2711882123085845,"score_spread":0.2502678874912541,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}