{"id":"W2754157379","doi":"10.1002/ejoc.201701143","title":"Directed <i>ortho</i>‐Metalation of Aryl Amides, <i>O‐</i>Carbamates, and Methoxymethoxy Systems: Directed Metalation Group Competition and Cooperation","year":2017,"lang":"en","type":"article","venue":"European Journal of Organic Chemistry","topic":"Coordination Chemistry and Organometallics","field":"Chemistry","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"","keywords":"Metalation; Chemistry; Electrophile; Aryl; Combinatorial chemistry; Stereochemistry; Competition (biology); Group (periodic table); Medicinal chemistry; Organic chemistry; Catalysis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00130443,0.0003018908,0.0005587872,0.00005844713,0.000327547,0.0002758709,0.0003250721,0.000119427,0.000514865],"category_scores_gemma":[0.001210491,0.0002980941,0.0001085053,0.0001449762,0.0002162305,0.0005402068,0.0001582394,0.0003862956,0.000002019757],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006371817,"about_ca_system_score_gemma":0.00005740044,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005897014,"about_ca_topic_score_gemma":0.000001546841,"domain_scores_codex":[0.9979705,0.0001091538,0.001035972,0.0003298658,0.0003677497,0.0001868167],"domain_scores_gemma":[0.9966174,0.0001956865,0.001988324,0.0004724925,0.0005381397,0.0001879019],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006427122,0.00008090778,0.003515961,0.0006075248,0.0001816982,0.0000300432,0.0001296461,0.000009541335,0.9937337,0.00007378009,0.00003373035,0.001539171],"study_design_scores_gemma":[0.002027225,0.00004480655,0.0157518,0.0005004713,0.0004371288,0.0005964048,0.0002323114,0.0008295315,0.9759361,0.0000345808,0.003207448,0.0004022147],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.98936,0.001965566,0.001071183,0.00009491228,0.0001270434,0.00007150445,0.00004018503,0.00009228808,0.0071773],"genre_scores_gemma":[0.9969063,0.0005900134,0.001408701,0.0000091744,0.0003025211,0.000001325429,0.0001200872,0.00005829295,0.0006035396],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01779765,"threshold_uncertainty_score":0.9999471,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01295500895030091,"score_gpt":0.2241287313551241,"score_spread":0.2111737224048232,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}