{"id":"W2754197885","doi":"10.1158/2326-6066.cir-17-0056","title":"Immunosurveillance and Immunoediting of Breast Cancer via Class I MHC Receptors","year":2017,"lang":"en","type":"article","venue":"Cancer Immunology Research","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University; University of Ottawa","funders":"","keywords":"Immunoediting; Immunosurveillance; Biology; MHC class I; Immune system; Cancer research; Major histocompatibility complex; NKG2D; Immunology; Cancer; Granzyme B; Immunotherapy; CD8; Cytotoxic T cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001330749,0.0001887436,0.0001531103,0.0001887118,0.00007969269,0.0002799618,0.0001674213,0.0002434322,0.001239465],"category_scores_gemma":[0.0001295342,0.00009010794,0.0001770185,0.0000594376,0.0001770147,0.0002635186,0.0002364325,0.0003753355,0.0004090292],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002059827,"about_ca_system_score_gemma":0.00008068686,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000189744,"about_ca_topic_score_gemma":0.0001803403,"domain_scores_codex":[0.9998274,0.00004253396,0.0000119075,0.0000217447,0.00003720752,0.00005917512],"domain_scores_gemma":[0.9998485,0.00003000057,0.0000532709,0.00002783324,0.00001434975,0.00002607775],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005769003,0.00001178188,0.0003645582,0.00001130787,0.000001322846,0.00003647626,0.000005455878,0.00003521403,0.9984634,0.00009942405,0.00001680974,0.0008965681],"study_design_scores_gemma":[0.00001558166,0.0003650098,0.009273186,0.000006793426,0.00000940733,0.0006106983,0.00004136475,0.001514522,0.9863855,0.00009040305,0.001683993,0.000003485652],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9942814,0.001329081,0.002783185,0.00007278667,0.00001263005,0.00001480732,0.000105344,0.00005860098,0.001342068],"genre_scores_gemma":[0.9981259,0.0003472192,0.0006270877,0.00001777915,0.000005776782,0.00000996417,0.00008450406,0.000008422468,0.0007734016],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001239465,"threshold_uncertainty_score":0.004146457,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04309160312057609,"score_gpt":0.3601351789880907,"score_spread":0.3170435758675146,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}