{"id":"W2754197885","doi":"10.1158/2326-6066.cir-17-0056","title":"Immunosurveillance and Immunoediting of Breast Cancer via Class I MHC Receptors","year":2017,"lang":"en","type":"article","venue":"Cancer Immunology Research","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University; University of Ottawa","funders":"","keywords":"Immunoediting; Immunosurveillance; Biology; MHC class I; Immune system; Cancer research; Major histocompatibility complex; NKG2D; Immunology; Cancer; Granzyme B; Immunotherapy; CD8; Cytotoxic T cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["sts","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000959162,0.0002583231,0.0005200481,0.0003193288,0.001833781,0.00007400178,0.0008116994,0.0004838985,0.004783079],"category_scores_gemma":[0.0002684277,0.0002412899,0.0001147179,0.0001759701,0.002590038,0.0004049993,0.0005967326,0.001400205,0.0002459848],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002398719,"about_ca_system_score_gemma":0.0002148318,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006305748,"about_ca_topic_score_gemma":0.0001819393,"domain_scores_codex":[0.9974084,0.0005958716,0.0005223508,0.0005388323,0.0001139531,0.0008205501],"domain_scores_gemma":[0.9973724,0.0002548112,0.000461553,0.001042104,0.0008381553,0.0000309042],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001455437,0.00008081249,0.03819579,0.0000559405,0.0005718462,0.000002779019,0.0003735652,0.000001616083,0.9193333,0.0001507771,0.00573978,0.0340384],"study_design_scores_gemma":[0.002906068,0.0002509133,0.6416697,0.0002672588,0.00003136592,0.0002466379,0.0009248023,0.00001247858,0.279624,0.00006832292,0.07363651,0.000361933],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9484165,0.03680927,0.00001002464,0.002687145,0.009135075,0.0003400449,0.00005408259,0.00005998558,0.00248787],"genre_scores_gemma":[0.9689918,0.01308222,0.000005681557,0.00004918331,0.0001376553,0.0001916618,0.00003450134,0.00003884641,0.01746845],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6397092,"threshold_uncertainty_score":0.9994657,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04309160312057609,"score_gpt":0.3601351789880907,"score_spread":0.3170435758675146,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}