{"id":"W2754249088","doi":"10.4049/jimmunol.196.supp.55.16","title":"Defining the role of Tim-3 in T cells","year":2016,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"École Nationale d'Administration Publique","funders":"","keywords":"Cytotoxic T cell; T cell; Immune system; Effector; Cell biology; Biology; Stimulation; IL-2 receptor; Ectopic expression; Immunology; T-cell receptor; In vitro; Neuroscience; Cell culture; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004936502,0.0003035728,0.0001461746,0.000377254,0.0002441823,0.0007618916,0.0002983547,0.0004951698,0.001245752],"category_scores_gemma":[0.0001732353,0.00008822775,0.0002953384,0.0002566815,0.0005026679,0.0008198754,0.0003519709,0.001046125,0.0005443157],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00075441,"about_ca_system_score_gemma":0.0003792988,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003558226,"about_ca_topic_score_gemma":0.0003554547,"domain_scores_codex":[0.9998645,0.00002771459,0.00001535882,0.00001940434,0.00002625762,0.000046809],"domain_scores_gemma":[0.9998993,0.00001315167,0.00002518068,0.00001173096,0.00002328322,0.00002746648],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004136779,0.00007975083,0.001420344,0.0003541634,0.00001810575,0.0001683343,0.00008505574,0.0002735304,0.9774484,0.005677935,0.0004110966,0.01364956],"study_design_scores_gemma":[0.00007267642,0.0007198055,0.01431017,0.0001467711,0.00008053351,0.001168561,0.0003134932,0.004070543,0.9307886,0.005708566,0.04259634,0.00002390654],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8998255,0.04950939,0.0350747,0.003881674,0.0005214178,0.0001700629,0.001247976,0.0001472507,0.009622049],"genre_scores_gemma":[0.9753876,0.01026889,0.01054839,0.0006374875,0.0001725613,0.00007028145,0.0005321,0.00001745674,0.002365223],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001245752,"threshold_uncertainty_score":0.005473673,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01307551642615321,"score_gpt":0.2875619280963081,"score_spread":0.2744864116701549,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}