{"id":"W2754310746","doi":"10.1124/pr.115.012062","title":"Connexins in Cardiovascular and Neurovascular Health and Disease: Pharmacological Implications","year":2017,"lang":"en","type":"review","venue":"Pharmacological Reviews","topic":"Connexins and lens biology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":247,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia; Western University","funders":"National Eye Institute; National Science Foundation; Canadian Institutes of Health Research; Vlaamse regering; Hungarian Scientific Research Fund; European Foundation for the Study of Diabetes; National Research, Development and Innovation Office; Universiteit Gent; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; National Institutes of Health; National Institute of General Medical Sciences; European Association for the Study of Diabetes","keywords":"Gap junction; Connexin; Connexon; Cell biology; Pannexin; Neuroscience; Biology; Myocyte; Cell type; Intracellular; Cell; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004984278,0.0009931793,0.001600538,0.001469217,0.0002873944,0.0009967126,0.0006866912,0.0009188111,0.004388858],"category_scores_gemma":[0.0006278935,0.0002485647,0.0004258643,0.001892388,0.0005006056,0.001367427,0.0008789892,0.001987947,0.001435864],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004064635,"about_ca_system_score_gemma":0.001037217,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008045902,"about_ca_topic_score_gemma":0.002147008,"domain_scores_codex":[0.9998674,0.00001977953,0.00002117752,0.0000247493,0.00004911566,0.00001774606],"domain_scores_gemma":[0.99976,0.0001048579,0.00003758679,0.000007559213,0.00005902297,0.00003102953],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001663814,0.00008740741,0.0001779102,0.01937925,0.000140141,0.0002648265,0.00007468349,0.0005170499,0.005402318,0.005641892,0.03869953,0.9294486],"study_design_scores_gemma":[0.00003761092,0.00009560667,0.0007302741,0.002778079,0.0002142766,0.0008950279,0.00008030247,0.0001408124,0.0007973011,0.00398566,0.9902151,0.00002995243],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001137784,0.9986327,0.0001497059,0.0002504834,0.0001859518,0.000003533625,0.00002007543,0.000006977421,0.0006366984],"genre_scores_gemma":[0.0005584309,0.9984654,0.0001789997,0.0001543533,0.0002070023,0.000004918204,0.00002238097,0.000001201691,0.0004073308],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004388858,"threshold_uncertainty_score":0.01468223,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1962248859841216,"score_gpt":0.450040531696715,"score_spread":0.2538156457125935,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}