{"id":"W2754310988","doi":"10.1371/journal.pone.0183662","title":"Inflammatory cytokine production in tumor cells upon chemotherapy drug exposure or upon selection for drug resistance","year":2017,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":72,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Sciences North; University of Ottawa; NOSM University; Laurentian University","funders":"","keywords":"Docetaxel; Cytokine; Tumor necrosis factor alpha; Pharmacology; TLR4; Drug resistance; Cancer research; Medicine; Immunology; Biology; Inflammation; Internal medicine; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001054114,0.0001918767,0.0002974586,0.0001601703,0.0001057024,0.0002607096,0.00006572498,0.0002047793,0.001114041],"category_scores_gemma":[0.0001447514,0.0001109927,0.0001780304,0.0002382608,0.0001436692,0.0002136263,0.0001436923,0.0003825938,0.0004148287],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001265831,"about_ca_system_score_gemma":0.00009376968,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001780177,"about_ca_topic_score_gemma":0.0002215803,"domain_scores_codex":[0.9998195,0.00003142628,0.00002194553,0.00003865993,0.00004732,0.00004123527],"domain_scores_gemma":[0.9998699,0.00002503828,0.00003238906,0.00002256896,0.000028039,0.00002202585],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002542562,0.00003460756,0.001044661,0.00003291276,0.000003537817,0.00009075369,0.00005321542,0.00003110161,0.9974335,0.00001804774,0.00002709347,0.0009764003],"study_design_scores_gemma":[0.00003607928,0.001809537,0.04510102,0.00001112777,0.0000291613,0.0007763087,0.0002403718,0.000801469,0.9487377,0.00004882518,0.002396383,0.00001199909],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965602,0.0009627823,0.0009560358,0.00004555693,0.00002617724,0.00003447371,0.0005457769,0.00002315413,0.0008458929],"genre_scores_gemma":[0.9941788,0.0009012088,0.001501372,0.00008175784,0.00001976599,0.000114864,0.001186964,0.000008642612,0.002006677],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001114041,"threshold_uncertainty_score":0.00372684,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01782811003587994,"score_gpt":0.226847913193151,"score_spread":0.2090198031572711,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}