{"id":"W2754445098","doi":"10.1136/annrheumdis-2017-eular.3718","title":"AB0627 Rise-ssc: a double-blind, randomised study evaluating the efficacy and safety of riociguat for the treatment of patients with diffuse cutaneous systemic sclerosis","year":2017,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Systemic Sclerosis and Related Diseases","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Western University","funders":"","keywords":"Riociguat; Medicine; Connective tissue disease; Fibrosis; Internal medicine; Placebo; Scleroderma (fungus); Gastroenterology; Clinical endpoint; Connective tissue; Surgery; Clinical trial; Pathology; Disease; Pulmonary hypertension; Autoimmune disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00228658,0.002024492,0.005938769,0.0009794898,0.0006343186,0.001027142,0.001466917,0.002549727,0.006776825],"category_scores_gemma":[0.002125253,0.001090809,0.001912331,0.0008188089,0.002538025,0.001482523,0.0005633907,0.003505722,0.001143189],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005437316,"about_ca_system_score_gemma":0.001418013,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00140031,"about_ca_topic_score_gemma":0.00211199,"domain_scores_codex":[0.9986086,0.000809418,0.00009942505,0.0001996582,0.00009239688,0.0001905124],"domain_scores_gemma":[0.9987458,0.0004580431,0.0001650599,0.0001224177,0.00008656845,0.0004221507],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.979704,0.006793867,0.0002306899,0.0005693265,0.0005491973,0.00004370598,0.00003285633,0.0001354277,0.003094662,0.0000737647,0.0002312489,0.008541178],"study_design_scores_gemma":[0.9377089,0.06079016,0.0006320627,0.00001442847,0.0002605079,0.00001619157,0.00001297494,0.0001529373,0.0002239207,0.00003442775,0.0001440814,0.000009507889],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9862493,0.004977278,0.0009935554,0.0004575185,0.0006135161,0.003797955,0.000706245,0.0002532584,0.001951387],"genre_scores_gemma":[0.9854693,0.003935889,0.001899185,0.00106003,0.000808122,0.003263847,0.0008638425,0.0000498253,0.002649975],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006776825,"threshold_uncertainty_score":0.02267081,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1164546058707738,"score_gpt":0.3576456307765168,"score_spread":0.241191024905743,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}