{"id":"W2754801730","doi":"10.21769/bioprotoc.2555","title":"Uptake Assays to Monitor Anthracyclines Entry into Mammalian Cells","year":2017,"lang":"en","type":"article","venue":"BIO-PROTOCOL","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hôpital Maisonneuve-Rosemont","funders":"","keywords":"Daunorubicin; Doxorubicin; DNA; Anthracycline; Chemistry; Pharmacology; Cancer research; Biology; Biochemistry; Chemotherapy; Cancer; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002177986,0.0002831336,0.000234365,0.00006283044,0.0004662185,0.0001688516,0.0005907288,0.0002669817,0.00001133813],"category_scores_gemma":[0.0001441185,0.0002333943,0.0001745583,0.00006261162,0.0001659239,0.00001006802,0.0003420939,0.0001034774,0.00005013062],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002284811,"about_ca_system_score_gemma":0.00003552069,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009770867,"about_ca_topic_score_gemma":0.00009725464,"domain_scores_codex":[0.9984828,0.00004463942,0.0003362142,0.0005954616,0.000192747,0.0003481999],"domain_scores_gemma":[0.998105,0.00000566017,0.0002562918,0.001291913,0.0001508735,0.0001902477],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001986928,0.0000979937,0.001105138,0.00003453333,0.00002901805,0.00001064606,0.000008526451,0.000001281081,0.944773,0.0000128514,0.01132136,0.04240691],"study_design_scores_gemma":[0.0003654232,0.0002258047,0.001518814,0.00002652129,0.00001029829,0.000002755943,0.00001640021,0.000008520426,0.6646673,0.0000593083,0.3328645,0.0002343954],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"protocol","genre_gemma":"empirical","genre_scores_codex":[0.1594599,0.00001790834,0.004162838,0.003188002,0.0007030657,0.8211141,0.0001339746,0.0004157634,0.01080446],"genre_scores_gemma":[0.5515072,0.000005721465,0.03245686,0.0004900894,0.001477632,0.4104721,0.00002790273,0.00005747217,0.003505056],"genre_candidate":"protocol","genre_consensus":null,"teacher_disagreement_score":0.410642,"threshold_uncertainty_score":0.9517542,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01675707941136164,"score_gpt":0.3540828371019775,"score_spread":0.3373257576906158,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}