{"id":"W2755104793","doi":"10.2147/opth.s141404","title":"In vitro release of two anti-muscarinic drugs from soft contact lenses","year":2017,"lang":"en","type":"article","venue":"Clinical ophthalmology","topic":"Ocular Surface and Contact Lens","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Medicine; Ophthalmology; In vitro; Pharmacology; Muscarinic acetylcholine receptor; Optometry; Internal medicine; Chemistry; Biochemistry; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002371462,0.0003474713,0.000260422,0.0001744247,0.0001112621,0.0002933949,0.0001470213,0.0002176087,0.001156823],"category_scores_gemma":[0.0002775555,0.000102931,0.0002239534,0.0001725673,0.0001120811,0.0002471191,0.000160838,0.0002343679,0.0002145745],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002203589,"about_ca_system_score_gemma":0.0001544865,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007492229,"about_ca_topic_score_gemma":0.00121966,"domain_scores_codex":[0.999755,0.00003237323,0.00002733798,0.00003173306,0.0001207974,0.00003283312],"domain_scores_gemma":[0.9997308,0.000105052,0.0000631885,0.00002121003,0.0000503677,0.00002936451],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001256655,0.0000194279,0.0001802847,0.00008288727,0.000008073574,0.00003784519,0.00001746495,0.0000297593,0.9982528,0.000005975771,0.000008158538,0.001231592],"study_design_scores_gemma":[0.00001161121,0.001062856,0.003928178,0.00000817095,0.00002177832,0.00008050515,0.00002873688,0.0002849777,0.9941214,0.000005277993,0.0004426779,0.000003784349],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995465,0.002648402,0.001084122,0.00001563513,0.00001857133,0.00002557343,0.0001361176,0.00001161424,0.0005949498],"genre_scores_gemma":[0.995089,0.001273287,0.00177223,0.00002021059,0.00001173155,0.00002364422,0.0002739188,0.00001028008,0.001525685],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001156823,"threshold_uncertainty_score":0.00387001,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06184499548881991,"score_gpt":0.4087304332423672,"score_spread":0.3468854377535473,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}