{"id":"W2755137651","doi":"10.1158/2326-6066.cir-17-0102","title":"Customized Viral Immunotherapy for HPV-Associated Cancer","year":2017,"lang":"en","type":"article","venue":"Cancer Immunology Research","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital; Children's Hospital of Eastern Ontario; McMaster University Medical Centre","funders":"Terry Fox Foundation","keywords":"Oncolytic virus; Immunotherapy; Cancer immunotherapy; Immunology; Immune system; Cancer; Vaccination; CD8; Virotherapy; Cancer research; Medicine; Tumor microenvironment; Cytotoxic T cell; Epitope; Priming (agriculture); Virology; Biology; Antibody; Internal medicine; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","sts","insufficient_payload"],"consensus_categories":["sts"],"category_scores_codex":[0.002669428,0.0004697675,0.0009584631,0.0004593909,0.004878584,0.0002380224,0.002519364,0.001017708,0.005100104],"category_scores_gemma":[0.001194645,0.0004234677,0.0004246133,0.0002062671,0.00309435,0.0004283453,0.0004248655,0.001559895,0.0005026453],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005794632,"about_ca_system_score_gemma":0.001040115,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004344961,"about_ca_topic_score_gemma":0.0002937156,"domain_scores_codex":[0.9950159,0.001337247,0.000665053,0.0008278331,0.0001551574,0.001998792],"domain_scores_gemma":[0.9955003,0.001120767,0.0004866067,0.001884641,0.0009680561,0.00003957875],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0134313,0.0003005884,0.002476841,0.00002292281,0.002682626,0.000005643337,0.0007580477,0.000002864679,0.8283388,0.001154119,0.0160566,0.1347696],"study_design_scores_gemma":[0.02173935,0.0009272022,0.06306399,0.0001722234,0.00007133552,0.00002202781,0.0003733848,0.00001442718,0.3695457,0.001239194,0.5421152,0.000716002],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8123315,0.1712689,0.00008992313,0.005740166,0.005629328,0.00200351,0.0003966544,0.0002211433,0.002318862],"genre_scores_gemma":[0.9024484,0.02290767,0.00003976886,0.0003508553,0.0001853612,0.003781299,0.0001206782,0.0001363767,0.07002959],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5260586,"threshold_uncertainty_score":0.9998217,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0796066015998657,"score_gpt":0.4180975750450982,"score_spread":0.3384909734452325,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}