{"id":"W2755137651","doi":"10.1158/2326-6066.cir-17-0102","title":"Customized Viral Immunotherapy for HPV-Associated Cancer","year":2017,"lang":"en","type":"article","venue":"Cancer Immunology Research","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital; Children's Hospital of Eastern Ontario; McMaster University Medical Centre","funders":"Terry Fox Foundation","keywords":"Oncolytic virus; Immunotherapy; Cancer immunotherapy; Immunology; Immune system; Cancer; Vaccination; CD8; Virotherapy; Cancer research; Medicine; Tumor microenvironment; Cytotoxic T cell; Epitope; Priming (agriculture); Virology; Biology; Antibody; Internal medicine; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001267804,0.0003821838,0.0002241322,0.0002311978,0.0001155456,0.0003563452,0.0002667092,0.0003333557,0.001946474],"category_scores_gemma":[0.00008650229,0.0001013243,0.0002029334,0.0001814548,0.0001676663,0.0002036278,0.0003545085,0.0006451689,0.0004584713],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003754577,"about_ca_system_score_gemma":0.0001971126,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002607967,"about_ca_topic_score_gemma":0.0003344444,"domain_scores_codex":[0.9998918,0.00001420525,0.000004985521,0.00002052246,0.00003537634,0.00003305592],"domain_scores_gemma":[0.9999638,0.000004089533,0.00001093973,0.000007737824,0.000004562587,0.000008894026],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009839016,0.0001636311,0.0001939851,0.0001035796,0.00001266249,0.00006264428,0.00002263837,0.00147159,0.9747342,0.00145286,0.000327345,0.0213565],"study_design_scores_gemma":[0.0001266905,0.002508894,0.001992437,0.00003420142,0.00006054757,0.0009724729,0.00002568104,0.007608159,0.942241,0.00111809,0.04329286,0.00001889794],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9433233,0.00891848,0.03734758,0.0003686819,0.0002712831,0.0004101438,0.0005026323,0.0006862105,0.008171738],"genre_scores_gemma":[0.9820269,0.003084613,0.01044059,0.000122089,0.00004529149,0.0001514153,0.0003371948,0.00003880934,0.003753206],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001946474,"threshold_uncertainty_score":0.006511629,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0796066015998657,"score_gpt":0.4180975750450982,"score_spread":0.3384909734452325,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}