{"id":"W2755505764","doi":"10.1136/annrheumdis-2017-eular.6119","title":"THU0388 Efficacy and safety of adalimumab in patients with non-radiographic axial spondyloarthritis: results from the 28-week open-label period of the ability-3 study","year":2017,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Spondyloarthritis Studies and Treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Toronto Western Hospital","funders":"Pfizer; Amgen","keywords":"Medicine; Adalimumab; BASDAI; Ankylosing spondylitis; Axial spondyloarthritis; Placebo; Internal medicine; Bristol-Myers; Randomized controlled trial; Physical therapy; Rheumatoid arthritis; Psoriatic arthritis; Sacroiliitis; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002707699,0.001169665,0.002895686,0.0003896678,0.0003770483,0.001120583,0.0008399464,0.00126919,0.001825019],"category_scores_gemma":[0.002111017,0.0004378441,0.002686061,0.0004799126,0.0008878722,0.00109294,0.0003944389,0.002512914,0.0006459142],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006854084,"about_ca_system_score_gemma":0.0009010278,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009566466,"about_ca_topic_score_gemma":0.001521548,"domain_scores_codex":[0.9987233,0.0006750526,0.0001116532,0.0001249649,0.0001611253,0.0002038925],"domain_scores_gemma":[0.9980691,0.0005781497,0.0005790878,0.0002071102,0.0001346401,0.0004318404],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.8935013,0.01079743,0.01705185,0.0007493468,0.002799266,0.000166534,0.0002169466,0.001069004,0.01109034,0.0001032468,0.001171403,0.06128335],"study_design_scores_gemma":[0.5136676,0.2976444,0.1763468,0.0001157733,0.003444357,0.0004974165,0.0002307039,0.002266733,0.00362966,0.0002209253,0.00179932,0.0001364008],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963174,0.002263611,0.0001315637,0.0001132101,0.00003322912,0.0001191742,0.0004774138,0.00003601109,0.0005082994],"genre_scores_gemma":[0.9976574,0.0006862296,0.0002573808,0.0001634602,0.00007554823,0.0001317948,0.0006137886,0.00001299436,0.0004013946],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002895686,"threshold_uncertainty_score":0.0143199,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03759944051422884,"score_gpt":0.3034550495326321,"score_spread":0.2658556090184032,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}