{"id":"W2755543134","doi":"10.21037/atm.2017.08.38","title":"Very early antiretroviral therapy permits CD8 T cells to keep HIV reservoirs at bay","year":2017,"lang":"en","type":"letter","venue":"Annals of Translational Medicine","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre","funders":"McGill University; Canadian Institutes of Health Research; Canadian Foundation for AIDS Research; Styrelsen för Internationellt Utvecklingssamarbete","keywords":"CD8; Antiretroviral therapy; Immunology; Human immunodeficiency virus (HIV); Immune system; Cytotoxic T cell; T cell; Medicine; Cell; Virus; Virology; Viral replication; Viral load; Biology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004621115,0.0003674431,0.0005096593,0.0002059104,0.0007025382,0.001014963,0.0004720433,0.00575171,0.004694483],"category_scores_gemma":[0.003288475,0.0001120627,0.0002758261,0.0001979049,0.0009465381,0.0008893624,0.0003743989,0.006286177,0.006730359],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007163737,"about_ca_system_score_gemma":0.0004282817,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003642687,"about_ca_topic_score_gemma":0.0004351464,"domain_scores_codex":[0.9994842,0.0002071765,0.00003488577,0.00005906805,0.0001349896,0.00007961418],"domain_scores_gemma":[0.9990181,0.000560402,0.00009306757,0.00006300703,0.0001331408,0.0001323058],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"observational","study_design_scores_codex":[0.0004786031,0.0001855515,0.005974314,0.0003882431,0.00003028964,0.05810845,0.000269927,0.0001951704,0.004795475,0.01385354,0.7281077,0.1876127],"study_design_scores_gemma":[0.0001500054,0.0002292668,0.001721677,0.0003147161,0.00002055812,0.04886875,0.0001885466,0.0006702072,0.001504913,0.01059226,0.9357193,0.00001991273],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"empirical","genre_scores_codex":[0.01740148,0.04135144,0.002401286,0.8568329,0.02951532,0.0001152887,0.0001771895,0.0004365252,0.05176857],"genre_scores_gemma":[0.1943874,0.04383688,0.002817779,0.5722748,0.1189347,0.0001273537,0.0002426416,0.0001361628,0.06724232],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.00575171,"threshold_uncertainty_score":0.01570463,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07845396378269005,"score_gpt":0.3376002186933896,"score_spread":0.2591462549106995,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}