{"id":"W2755746269","doi":"10.1039/c7ra07960e","title":"Sequential one-pot three-step synthesis of polysubstituted 4-(5-(trifluoromethyl)-1H-pyrazol-4-yl)-1H-1,2,3-triazole systems","year":2017,"lang":"en","type":"article","venue":"RSC Advances","topic":"Click Chemistry and Applications","field":"Chemistry","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"Conselho Nacional de Desenvolvimento Científico e Tecnológico; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior","keywords":"Trifluoromethyl; One-pot synthesis; Chemistry; Combinatorial chemistry; Triazole; Medicinal chemistry; Stereochemistry; Organic chemistry; Catalysis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002361856,0.0003630597,0.000663988,0.00005780112,0.0007095161,0.0001646466,0.001254024,0.0002804613,0.0006289284],"category_scores_gemma":[0.0005904468,0.0003707728,0.000243361,0.0001437227,0.0004620072,0.0004809159,0.0002066506,0.0003077235,0.000081276],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009254931,"about_ca_system_score_gemma":0.0001065594,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004556715,"about_ca_topic_score_gemma":0.0001362556,"domain_scores_codex":[0.9976522,0.00001863849,0.0007145206,0.0006354823,0.0004959179,0.0004832532],"domain_scores_gemma":[0.9965055,0.00039985,0.0009285478,0.001800916,0.0001642954,0.0002008834],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001098464,0.0003318187,0.00299017,0.0009158328,0.00022381,0.00001200852,0.00004123075,0.0001870284,0.9705972,0.002290838,0.0002757176,0.02202451],"study_design_scores_gemma":[0.0006036185,0.00001078843,0.0003634947,0.0003682888,0.0001736078,0.00001515055,0.0001563073,0.0004316937,0.9572344,0.0005357533,0.03967794,0.0004289876],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9057473,0.005519199,0.002657446,0.0004797914,0.0005732585,0.0004057118,0.0009063614,0.0003542034,0.08335675],"genre_scores_gemma":[0.9955189,0.0005098123,0.001074762,0.000009464286,0.0007246624,0.0002387197,0.00006103391,0.00004583577,0.001816799],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08977163,"threshold_uncertainty_score":0.9998744,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0350530679830393,"score_gpt":0.2985842834821628,"score_spread":0.2635312154991235,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}