{"id":"W2755771303","doi":"10.1007/s11010-017-3192-9","title":"Purification and characterization of skeletal muscle pyruvate kinase from the hibernating ground squirrel, Urocitellus richardsonii: potential regulation by posttranslational modification during torpor","year":2017,"lang":"en","type":"article","venue":"Molecular and Cellular Biochemistry","topic":"Adipose Tissue and Metabolism","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":false,"ca_institutions":"Carleton University; Ottawa Hospital","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Torpor; Ground squirrel; Skeletal muscle; Hibernation (computing); Biology; Glycolysis; Pyruvate kinase; Kinase; Biochemistry; Enzyme; Endocrinology; Thermoregulation","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001743192,0.0005257123,0.0003241381,0.0002688776,0.0003353185,0.0004897364,0.0002613221,0.0002330403,0.0005068876],"category_scores_gemma":[0.0002148119,0.0002230082,0.0002894938,0.0002914579,0.000283318,0.0004369431,0.0002424729,0.0005010596,0.0004519754],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003333382,"about_ca_system_score_gemma":0.0003381396,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003661568,"about_ca_topic_score_gemma":0.005434616,"domain_scores_codex":[0.9999105,0.000007687952,0.000008353245,0.00003084748,0.00001378734,0.0000287737],"domain_scores_gemma":[0.9998339,0.00002669295,0.00003351544,0.00002788512,0.00003745485,0.0000404824],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003439147,0.00003754435,0.002152077,0.00006120082,0.00001255767,0.0001221557,0.00009610921,0.00007858446,0.9950564,0.00007996827,0.00006831744,0.001891225],"study_design_scores_gemma":[0.0001053527,0.001152199,0.3003123,0.00004073644,0.0001295687,0.001708448,0.0008499157,0.002201733,0.6821961,0.0003867245,0.01087286,0.00004412416],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9951851,0.001702964,0.001112734,0.000192912,0.00003574676,0.0000226433,0.0009781176,0.00001496284,0.0007549158],"genre_scores_gemma":[0.982369,0.001266389,0.003135774,0.0001541697,0.00005753433,0.00003038851,0.007937955,0.00003848612,0.005010382],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003661568,"threshold_uncertainty_score":0.007280529,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00803519229313895,"score_gpt":0.2221975593474909,"score_spread":0.2141623670543519,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}