{"id":"W2755992067","doi":"10.1097/aln.0000000000001861","title":"Disruption of Hippocampal Multisynaptic Networks by General Anesthetics","year":2017,"lang":"en","type":"article","venue":"Anesthesiology","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research","keywords":"Excitatory postsynaptic potential; Perforant path; Isoflurane; Pentobarbital; Medicine; Inhibitory postsynaptic potential; Postsynaptic potential; Population; Population spike; Anesthesia; Long-term potentiation; Local field potential; Hippocampal formation; Hippocampus; Neuroscience; Internal medicine; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002422129,0.0001593992,0.0002711458,0.00007270505,0.0005485713,0.00004423808,0.001028408,0.0001436865,0.0000612088],"category_scores_gemma":[0.0005255292,0.0001361401,0.00007362883,0.0000882048,0.001590009,0.0001870156,0.0001709264,0.000282737,0.00006553666],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001044317,"about_ca_system_score_gemma":0.0000336838,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002765457,"about_ca_topic_score_gemma":0.000001479406,"domain_scores_codex":[0.9981239,0.0003870254,0.0002505436,0.0005250283,0.0001933872,0.0005200858],"domain_scores_gemma":[0.9986581,0.000315478,0.0002395344,0.0006295811,0.00003532695,0.0001220482],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001058336,0.0001223707,0.04033612,0.000006046806,0.000001459036,0.0002928742,0.00002999044,0.00007221824,0.9543937,0.0006808973,0.000628913,0.003329508],"study_design_scores_gemma":[0.001163516,0.001574535,0.1315363,0.00001019593,0.00002238107,0.0009028308,0.00001103117,0.01541038,0.8428089,0.0007148832,0.005475973,0.0003691201],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9987808,0.00004816894,0.00004280292,0.0003708252,0.0003296029,0.0001975415,0.000004328352,0.00003741011,0.0001884718],"genre_scores_gemma":[0.9976549,0.0004286609,0.00002378699,0.001256269,0.0000798467,0.00001958086,0.000001094434,0.00001975337,0.0005161595],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1115849,"threshold_uncertainty_score":0.5858456,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05058615129846089,"score_gpt":0.3484422531013178,"score_spread":0.2978561018028569,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}