{"id":"W2755992067","doi":"10.1097/aln.0000000000001861","title":"Disruption of Hippocampal Multisynaptic Networks by General Anesthetics","year":2017,"lang":"en","type":"article","venue":"Anesthesiology","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research","keywords":"Excitatory postsynaptic potential; Perforant path; Isoflurane; Pentobarbital; Medicine; Inhibitory postsynaptic potential; Postsynaptic potential; Population; Population spike; Anesthesia; Long-term potentiation; Local field potential; Hippocampal formation; Hippocampus; Neuroscience; Internal medicine; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001005493,0.0003781434,0.0002167264,0.000160109,0.0001046074,0.0001419734,0.0002270137,0.0001403998,0.000647274],"category_scores_gemma":[0.000136052,0.00008757112,0.0001975603,0.00007974248,0.0002133309,0.000190774,0.0001866352,0.0003273726,0.0001080782],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002840875,"about_ca_system_score_gemma":0.000213973,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009531403,"about_ca_topic_score_gemma":0.002239342,"domain_scores_codex":[0.9999148,0.00001029447,0.000008060077,0.00001304494,0.00002413548,0.0000296731],"domain_scores_gemma":[0.9998825,0.00001098948,0.0000559117,0.00001252087,0.00001659239,0.00002160039],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003902454,0.00003442574,0.0007211097,0.00005789888,0.00001918157,0.00006105154,0.00001195934,0.00008899473,0.9955141,0.00004914798,0.00003560399,0.003016312],"study_design_scores_gemma":[0.00006301694,0.002184087,0.06770476,0.00002829096,0.0001128912,0.0005844481,0.00009329898,0.001249174,0.9265879,0.0001497146,0.001232564,0.000009700158],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996408,0.001833302,0.0011115,0.00005390937,0.00001021471,0.00001956169,0.0000999518,0.00004166897,0.0004218197],"genre_scores_gemma":[0.9968197,0.001660192,0.0008785864,0.0000468757,0.000006783326,0.00003095675,0.0001764787,0.00000791993,0.0003724445],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009531403,"threshold_uncertainty_score":0.002165377,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05058615129846089,"score_gpt":0.3484422531013178,"score_spread":0.2978561018028569,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}