{"id":"W2756174617","doi":"10.1111/dom.13114","title":"Efficacy and safety of alirocumab in insulin‐treated individuals with type 1 or type 2 diabetes and high cardiovascular risk: The <scp>ODYSSEY DM‐INSULIN</scp> randomized trial","year":2017,"lang":"en","type":"article","venue":"Diabetes Obesity and Metabolism","topic":"Diabetes Treatment and Management","field":"Medicine","cited_by":140,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"Regeneron Pharmaceuticals; Sanofi","keywords":"Alirocumab; Medicine; Internal medicine; Type 2 diabetes; Endocrinology; Placebo; Type 1 diabetes; Cholesterol; Insulin; Diabetes mellitus; PCSK9; Population; Apolipoprotein B; Lipoprotein; Apolipoprotein A1; LDL receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001596624,0.001267529,0.001951855,0.0003214531,0.0004129569,0.001079162,0.0005384835,0.001346751,0.004062578],"category_scores_gemma":[0.001885105,0.0004244875,0.001655541,0.0002658232,0.0007212235,0.0005939688,0.0003571036,0.001912361,0.0004929916],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000561911,"about_ca_system_score_gemma":0.0007383079,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00114636,"about_ca_topic_score_gemma":0.002391219,"domain_scores_codex":[0.9993993,0.0003413314,0.00004827725,0.00009422751,0.00004777422,0.00006907599],"domain_scores_gemma":[0.9992164,0.0001661527,0.0002649815,0.00005293443,0.00005481658,0.0002446361],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.982357,0.002265527,0.002330612,0.0005590064,0.001092404,0.00003591679,0.00002725537,0.0001323298,0.001129607,0.00006554968,0.0005682269,0.009436537],"study_design_scores_gemma":[0.9639509,0.02692662,0.006250244,0.00007197974,0.001354648,0.00007001129,0.0000196608,0.0003857816,0.0002994343,0.0001079169,0.0005496995,0.00001310024],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9885879,0.006143115,0.0002628033,0.0007008813,0.0003441999,0.001246685,0.0006114044,0.00004770564,0.002055266],"genre_scores_gemma":[0.9904181,0.002841755,0.0007942934,0.00112056,0.0004602848,0.001600659,0.0008808817,0.00001157818,0.001871855],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004062578,"threshold_uncertainty_score":0.01359063,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01075347439363494,"score_gpt":0.2304660606959438,"score_spread":0.2197125863023089,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}