{"id":"W2756408218","doi":"10.1038/s41598-017-12262-1","title":"CRISPR/Cas9-induced Targeted Mutagenesis and Gene Replacement to Generate Long-shelf Life Tomato Lines","year":2017,"lang":"en","type":"article","venue":"Scientific Reports","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":254,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Genetics; Special Fund for Agro-scientific Research in the Public Interest","keywords":"CRISPR; Cas9; Biology; Mutagenesis; Gene; Genome editing; Genetics; Transgene; Mutant; Genotyping; Genetically modified crops; Transformation (genetics); Computational biology; Biotechnology; Genotype","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007103461,0.0002277855,0.0002070926,0.00009041814,0.0006381511,0.0005076329,0.0002348944,0.0001195815,0.00003290314],"category_scores_gemma":[0.0004417264,0.0002194284,0.00008197896,0.00008511748,0.00008716946,0.00001039235,0.0003802078,0.00005441314,0.00001258825],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001249329,"about_ca_system_score_gemma":0.0001102453,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000480085,"about_ca_topic_score_gemma":0.00007802102,"domain_scores_codex":[0.9978855,0.00002300558,0.0004053327,0.001031555,0.0002725333,0.0003820376],"domain_scores_gemma":[0.9974383,0.000003764482,0.0001958273,0.00181372,0.0001826082,0.000365809],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002003494,0.0000316379,0.005322829,0.00002296075,0.00004261115,0.0001368764,0.00006627037,0.0004469196,0.9844028,0.000001426459,0.008095989,0.001409661],"study_design_scores_gemma":[0.0001796798,0.0000906255,0.01493452,0.0000140781,0.00002545817,0.0001997264,0.00002712192,0.0002642701,0.9664249,0.00001962566,0.01752248,0.000297506],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9898266,0.0009532067,0.0043333,0.000281088,0.004055962,0.0003405146,0.000006204178,0.00003241179,0.0001707713],"genre_scores_gemma":[0.993749,0.00003366802,0.0020973,0.0001056546,0.0003657094,0.00004454979,0.00007496285,0.00003264445,0.003496499],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01797788,"threshold_uncertainty_score":0.8948029,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01462372681573957,"score_gpt":0.3071549349144105,"score_spread":0.2925312080986709,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}