{"id":"W2756573149","doi":"10.1021/acs.iecr.7b02872","title":"Noncovalent Immobilization of Optimized Bacterial Cytochrome P450 BM3 on Functionalized Magnetic Nanoparticles","year":2017,"lang":"en","type":"article","venue":"Industrial & Engineering Chemistry Research","topic":"Enzyme Catalysis and Immobilization","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Biocatalysis; Chemistry; Hydroxylation; Cofactor; Adsorption; Context (archaeology); Enzyme; Immobilized enzyme; Active site; Combinatorial chemistry; Catalysis; Organic chemistry; Reaction mechanism; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001128923,0.0002866335,0.0001554056,0.0001185947,0.0001066541,0.0001441379,0.0002169688,0.0002327436,0.0005019686],"category_scores_gemma":[0.0001279859,0.0001006574,0.0001960514,0.0001109992,0.0001093567,0.0001268881,0.0001457241,0.0002274429,0.000237918],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002705583,"about_ca_system_score_gemma":0.0000922023,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007704173,"about_ca_topic_score_gemma":0.001268206,"domain_scores_codex":[0.9998866,0.00001740639,0.000008438871,0.00002870553,0.00003565069,0.00002310367],"domain_scores_gemma":[0.9999653,0.000005396956,0.000009121685,0.000004326315,0.000009660973,0.000006082214],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001221922,0.00000553072,0.00003551551,0.00001258457,0.000002077645,0.000007348735,0.00000297821,0.00004679409,0.9993438,0.00002114272,0.00001105637,0.0004989541],"study_design_scores_gemma":[0.000001991544,0.00004201474,0.0003793099,0.000001093117,0.0000046231,0.00002061016,0.000004265064,0.0006846476,0.9983836,0.00000820967,0.0004677154,0.000001767589],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.988812,0.0004602256,0.009580676,0.00005409784,0.00001699626,0.00001821921,0.00006405545,0.00006545102,0.0009284285],"genre_scores_gemma":[0.9910163,0.0002526999,0.006938607,0.0000214754,0.000005345521,0.00001820772,0.0001609908,0.00001568802,0.001570598],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007704173,"threshold_uncertainty_score":0.001963079,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06441696210848982,"score_gpt":0.3255149082043807,"score_spread":0.2610979460958909,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}